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Team:Warsaw/Glossary
From 2009.igem.org
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(New page: {{WarHead1}} __NOTOC__ ==Glossary== ====apoptosis==== <div class="glossary_text">Apoptosis is a natural process of programmed cell death. Apoptosis can be induced by many factors and it...) |
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| - | <div class="glossary_text">Apoptosis is a natural process of programmed cell death. Apoptosis can be induced by many factors and its function is to remove damaged and unnecessary cells from the organism. In our project we want to induce apoptosis of tumor cells, using p53 or bax proteins, both involved in control of this process</div> | + | <div class="glossary_text">Apoptosis is a natural process of programmed cell death. Apoptosis can be induced by many factors and its function is to remove damaged and unnecessary cells from the organism. In our project we want to induce apoptosis of tumor cells, using [https://2009.igem.org/Team:Warsaw/Glossary#p53 p53] or [https://2009.igem.org/Team:Warsaw/Glossary#bax bax] proteins, both involved in control of this process</div> |
====bax==== | ====bax==== | ||
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| + | <div class="glossary_text">Bcl-2–associated X protein (bax) is a pro-apoptotic protein. Although it's found mainly in the cytosol, upon initiation of [https://2009.igem.org/Team:Warsaw/Glossary#apoptosis apoptosis] it's shifted to organellar membranes. It's believed that bax is responsible for opening special channels in the mitochondrial outer membrane, causing release of pro-apoptotic factors like cytochrome c. | ||
====cro==== | ====cro==== | ||
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====p53==== | ====p53==== | ||
| - | p53 is a protein well-known for people interested in cancer. p53 is a tumor suppressor and main factor involved in control of cell-cycle, mutated in more than half of tumors. Some data shows that presence of p53 in mitochondria is able to induce apoptosis. | + | p53 is a protein well-known for people interested in cancer. p53 is a tumor suppressor and main factor involved in control of cell-cycle, mutated in more than half of tumors. Some data shows that presence of p53 in mitochondria is able to induce [https://2009.igem.org/Team:Warsaw/Glossary#apoptosis apoptosis]. |
====phoP/PhoQ==== | ====phoP/PhoQ==== | ||
Revision as of 17:59, 13 August 2009
Glossary
apoptosis
Apoptosis is a natural process of programmed cell death. Apoptosis can be induced by many factors and its function is to remove damaged and unnecessary cells from the organism. In our project we want to induce apoptosis of tumor cells, using p53 or bax proteins, both involved in control of this process
bax
Bcl-2–associated X protein (bax) is a pro-apoptotic protein. Although it's found mainly in the cytosol, upon initiation of apoptosis it's shifted to organellar membranes. It's believed that bax is responsible for opening special channels in the mitochondrial outer membrane, causing release of pro-apoptotic factors like cytochrome c.
cro
cro-box
endosome
invasin
lacI
listeriolysin
mgtc promoter
p53
p53 is a protein well-known for people interested in cancer. p53 is a tumor suppressor and main factor involved in control of cell-cycle, mutated in more than half of tumors. Some data shows that presence of p53 in mitochondria is able to induce apoptosis.
