Team:BCCS-Bristol/Project

From 2009.igem.org

Revision as of 23:36, 7 July 2009 by Sr8243 (Talk | contribs)

BCCS-Bristol
iGEM 2009

Outer Membrane Vesicles

We are attempting to express (non-toxic!) heterologus proteins in bacterial outer membrane vesicles for the purposes of 'digital' communication, swarm immunity and pattern formation:

BCCS-Bristol vesicles.jpg

  • [http://dx.doi.org/10.1111/j.1365-2958.2006.05272.x Special delivery: vesicle trafficking in prokaryotes] (image credit)
  • [http://dx.doi.org/10.1016/j.jmb.2008.03.076 Engineered Bacterial Outer Membrane Vesicles with Enhanced Functionality]

Magnetotaxis

Inspired by papers on [http://link.aip.org/link/?APPLAB/89/233904/1 controlled manipulation and actuation of micro-objects with magnetotactic bacteria], we are also looking into magnetotaxis via attatchment of bacteria to external magnetic particles:

BCCS-Bristol Bead.jpg

  • [http://link.aip.org/link/?APPLAB/93/223901/1 Effect of quantity and configuration of attached bacteria on bacterial propulsion of microbeads] (image credit)
Retrieved from "http://2009.igem.org/Team:BCCS-Bristol/Project"