Team:SJTU-BioX-Shanghai
From 2009.igem.org
Project introduction. Inspired by the natural regulator of circadian bioclock exhibited in most eukaryotic organisms, our team has designed an E.coli-based genetic network with the toxin-antitoxin system so that the bacterium oscillates between two states of dormancy and activity (more...)
An E.coli-based oscillator of prokaryotic bioclock
Inspired by the natural regulator of circadian bioclock exhibited in most eukaryotic organisms, our team has designed an E.coli-based genetic network with the toxin-antitoxin system so that the bacterium oscillates between two states of dormancy and activity. Potential applications of this project include the preservation of frequently-mutating bacteria, biologic timing, antibiotic resistance, etc.