Team:BCCS-Bristol/Modeling
From 2009.igem.org
BCCS-Bristol
iGEM 2009
iGEM 2009
Contents |
Workflow
- Study Team:BCCS-Bristol/Modeling/Ideas to understand high level development goals (you can add stuff to that page!)
- Decide the specifics of what needs to be done and add items to your to-do list. Ideally the items added should read like commit messages
- Commit to the [http://code.google.com/p/bsim-bccs/ subversion repository] and
strike outthe item on your to-do list, adding a reference to the commit number if possible e.g:-
Rename BSimObject to BSimParticler19
-
Todo list
Steve
- Meet Sean Davies Monday 7th Aug re: beads - try to bring some polystyrene beads
- Learn something more about bioscaffolds
- Contact Paris team re:video
- Decide whether we are talking at the synbio conference, if so, who is talking
- Identify what batch simulations we wish to carry out asap. See [1].
- If our paradigm is particle dynamics, interactions with solid boundaries (that have a shape) are making things more complicated than neccesary.. traer physics is proving a big inspiration, it's beautifully simple - following its lead I believe we could dramatically decrease the complexity of the bsim physics engine
- Don't we only need _real_ physics between bacteria and beads..?
- Study whether 3D implementation of newPosition in BSimBacteriaCreate is reasonable r28
- 3D tumbling in BSimBacteria r30
- 3D diffusion for BSimChemicalField r29
- 3D boundaries r34
- Remove author, date from headers?
- Further refactoring to achieve clear and consistent class-package naming: make toolbar a nested class of app?
- Are PART_PART, PART_BACT, PART_BEAD really neccesary?
- Add paper references to parameter values in the code using page from last year
Mattia
- Last Year Bug Fixing:
New solution for reading gammaVals.txt (Old Problem: In Windows Vista semeed to be some reading problems)Mathematic corrections in calcDistFromBoundary(Wrong Mathematics)
- BSim 3D:
- Update Class BSimParticle r28 r51
Class parametersConstructorsetPositionsetCentrePossetDirectionnormalise3DVector
- Update Class BSimChemicalField r29 r35
Class parametersConstructorsetAsLinearredrawupdateField- Update Class BSimChemicalFieldThread
Class parametersConstructorrun
addChemicalgetConcentrationgetField
- Update Class BSImBacterium r30 r50 r55
iterateBacterium- iterateTumble
startNewPhasedoRun
- Update Class BSImBacteriaCreate r31 r48
createBacteriaSetcreateBacterium
- Update Class BSimDeadBacterium r32
runLogic
- Update Class BSimBeadsCreate r33
createBeadSetcreateBead
- Update Class BSimChemicalFieldCreate r36
createChemicalField
- Update Class BSimCollisionPhysics r37 r39 r46
Class parametersupdateProperties- Update Class BSimCollisionPhysicsThread
rundistBetweenPointsresolveExternalForceslinearMotionforce2Velocity3D
- Update Class BSimParameters r38 r41 r42 r58
- Update Class BSimScene r40 r56
resetScenerunAllUpdates
New Class BSimPlaneBoundaryCreater43 r 54New Class BSimSolidPlaneBoundaryr44 r49 r53- Update Class BSimParametersLoader r47 r57
processLine
New Class BSimWrapPlaneBoundaryr52
- Update Class BSimParticle r28 r51
Emily
- Fix BSim bug (short description here please :)
- Understand how bacteria "tumble" under magnetic force
- Finish coding the magnetic force
- Code half-coated bead
Antos
- GRNs and vesicles
- Read more about the mechanics of different GRNs (specifically switches).
- Find out how they interact with the external environment.
- Investigate the possiblity of using a different time-step to the fixed one in BSim.
- Investigate the effect of different time steps (GRNs operate on a time scale relatively long compared to that of BSim).
- Investigate the mechanics of our GRNs with respect to vesicle budding and communication.
- Investigate methods for numerically solving stochastic ODEs.
- BSim GRNs
-
Java implementation of Runge-Kutta 4th order solver. - Implement the solver into BSim.
- Implement other solvers (more efficient) and the ability to choose between them.
- Extend to Stochastic ODEs.
- Interface BSim with external parameters (maybe similar to current parameter files) used to define an ODE system.
- Investigate and implement GRN (ODE) and chemical field interaction.
- GRN interaction with vesicle budding and chemical transport (on the surface of the vesicle and inside it).
- Incorporate a method for seeing the effects of GRN activity (eg colour changes, pop-out time series).
-