Team:Imperial College London

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The E.ncapsulator

For iGEM 2009 the Imperial College London team present you with The E.ncapsulator; a versatile manufacture and delivery platform by which therapeutics can be reliably targeted to the intestine.

Our E.coli chassis progresses through a series of defined stages culminating in the production of a safe, inanimate pill. This sequential process involves drug production, protective encapsulation and genome deletion. The temporal transition between each of these stages is coordinated by both chemical and physical cues.

The E.ncapsulator provides an innovative method to deliver any biologically synthesisable compound and bypasses the need for expensive storage, packaging and purification processes. The E.ncapsulator is an attractive candidate for commercial pill development and demonstrates the massive manufacturing potential in Synthetic Biology.



Pushed for time? These links may be useful to quickly browse our results and achievements:

Major Results
Submitted Parts
Achievements
Pill Manufacture
Genealogy
 

Click below to begin a tour of the project
and its modules in more detail:


Mr. Gene   Geneart   Clontech   Giant Microbes