Team:USTC/Notebook/Brainstorming

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Team:USTC/Notebook/Brainstorming

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2009-02-10

Brainstorming began on our forum. More than 70 threads and 200 posts of ideas and discussions have been posted since then.

[http://biotech.ustc.edu.cn/forum/forumdisplay.php?fid=34 Visit Our Brainstorming Subforum]

2009-03-07

We did brainstorming on the team meeting, the following ideas were mentioned.


  • 产生某种物质 (produce something)
    • 让细菌产生氧气 (produce oxygen)
    • 细菌空气清新试剂盒 (air-freshing kit)
      • 散发不同的气味 (emit diverse smell)
    • 细菌产生胰岛素 (insulin-related production)
    • 改造乳酸菌防止蛀牙,可以在鲜奶中 (reconstructed lactobacillus to prevent decayed tooth, add to fresh milk)
    • 磁性蛋白 (magnetic protein)
  • 降解物质或污染治理 (degradation or pollution abatement)
    • 细菌降解有机垃圾 (degradation of organic trash)
    • 分解胆固醇 (decompose cholesterol)
    • 重金属处理 (heavy metal disposal)
    • 处理重金属,细菌的矿化作用 (mineralization of bacteria)
    • 金属聚集,产生沉淀体 (metal aggregation and deposition)
    • 生态环境,沙漠,细菌改造 (reconstruct bacteria, ecosystem, desert)
    • 多孔 (porous)
  • 传感器 (sensor)
    • 检测各种东东的 (check)
      • 检测酒精 (alcohol)
    • 感光的,城市 照明系统 (light-sensitive, switch of city illumination system)
    • 感应煤气 (gas-sensitive)
    • 感应磁场,细菌感应地磁场 (geomagnetism-sensitive)
    • 细菌群体条件反射 (group-based conditioned reflex)
    • 图像处理,可以让细菌对光强和光梯度敏感 (image processing)
    • 大肠杆菌感受某种味道 (certain smell-sensitive)
    • 做一个有味觉功能的细胞,氢氰酸有味道 (hydrocyanic acid smell)
    • 图像锐化 (image sharpening)
    • PS (photoshop)
  • 药物 (medicine)
    • 改造细菌,让细菌缓释药物?(drug slow-release by bacteria)
      • 缓释药物 (slow-release)
      • 药物靶向 (drug targeting)
    • 治疗血栓 (thrombi)
    • 染色体,基因治疗 (chromosome, gene therapy)
    • 预防蛀牙,预防流感 (prevent decayed tooth, flu)
  • dry
    • 古细菌,模拟(Archaebacteria)
    • 干实验,遗传算法(genetic algorithm)
    • 细胞来模拟,微波炉,有加热属性(simulant microwave oven)
    • 建筑物,鸟巢,鸟腿,鸟蛋,鸟人?(similar to buildings?)
    • 虚拟化(virtualization)
    • bioCAD,借鉴,原创性)(bioCAD,originality)
    • 经验的方法,总结前面的工作(summary of former works)
    • 先找一种硬纸?
    • 软件,进化软件(evolve software)
    • 单片机(SCM)
    • 综合各种感受细菌,连接起来,构成电路,再机器人(sensor——circuit——robot)
    • 设计滤波器(filter)
    • 控制问题,生物语言?(controling,bio-language)
    • bioCAD
  • 通讯(communication)
    • 真核与原核通讯(communication between eukaryon and procaryote)
    • 群落之间的交互过程(communication between communities)
    • 人菌通讯,光通讯(communication between people and bacteria)
      • 输出,光,电信号,原电池,产生某种离子,电导变化(output:light, electric signal, certain ion)
      • 光编码信息,让细菌感受(information coded by lights)
      • 用DNA存储信息,修改DNA存储信息(modify the information in DNA)
    • 细胞编程,群体协作,人和 细菌通讯(bio-programme,colony corperation)
    • 细菌在多种状态之间变化(states transation of bacterium)
    • 动力学状态,存储多个变量(dynamic states)
    • 敏感的光感细菌(light-sensing)
  • 其它
    • 模拟趋化运动(Chemotaxis and motility )
    • 酶的保存(preservation of enzyme)
      • 热休克蛋白(heat-shock protein;HSP)
    • 细胞周期代数计数或计时(calculation based on cell cycle)
      • 细胞做成时钟(bio-clock)
    • 利用 分子浓度梯度运输(transportation based on concentration gradient)
    • 细菌长出美丽的图形,细胞的图形(images)
    • 每个半小时变一次颜色(color change)
    • 完成某种功能,又不想继续保留(timely clearup)
      • 解耦联(Uncoupling)
      • 细菌洗头(washing)
    • 细菌模拟 认知网络(aware network )
    • 分形图案(fractal images)
    • 蛋白质折叠,需要其它蛋白辅助,蛋白消灭(protein folding, assistant protein, die out)
    • 生气的细胞,和快乐的细胞(angry and happy bacteria)
    • 模拟人生,情绪,高兴,低落?(The Sims,human life, emotion)
    • 染色体蛋白和DNA结合在一起(DNA combined with chromosome protein)
    • 寻宝?飞机黑匣子(treasure hunt)
    • 干细胞分化(stem cells differentiation)
    • 简单的biobrick,1,biobrick,魔术(magics)
  • 能源
    • 太阳能电池,微生物发电(electric generation)
    • 太阳能(solar energy)
    • 细胞发电(cell energy)
    • 调控细菌运动,细菌体内,两端,磁铁发电器(movement, magnet)
    • 细菌做功
    • 可再利用,能源(recycling energy)
    • 电鳗能同时诱导大量的细胞发电(numbfish)
    • 电鳗发电
    • 细菌发电,感受信号(electric signal sensing)
  • 进化或分化(evolution or differentiation)
    • 分子机器,利用基础蛋白实现自动化功能,自动分子克隆,热休克蛋白(molecular machine: automatic functions like molecular clone and heat shock on the basis of protein)
    • 模式形成,细胞分化(mode of differentiation)
    • 达尔文,自动定向进化机器(Darwin, automatic directed evolution)
    • 只有突变没有筛选(system with mutation and without filtration)
    • 达尔文进化一维的局限,多维多步骤进化(multi-dimension and multi-progress of evolation)
  • 特定功能(certain functions)
    • 周期性(periodicity)
    • 大肠杆菌周期节律(living cycle of E.coli)
    • 温度设定,温控?(temperature sensor)
    • 细菌保温,细菌恒温?(heat preservation by bacteria)
    • 舞蹈细菌,娱乐的,宠物细菌(dancing bacteria for entertainment)
    • 对家庭的模拟,模拟人生 (life and family simulation)
    • 数字图像加密,以光作为输入,化学印迹(encrypt on digital images, light as input and chemical print)
    • 噪声滤波?控制,滤掉噪声(filtration of noise)

2009-03-22

Ideas were narrowed down to the following 6 project options, and discussed on the [http://biotech.ustc.edu.cn/forum/forumdisplay.php?fid=64 Project Options Subforum].

  • Cell density control
  • Biological degradation of plastics
  • Light sensor
  • Reporter and imaging
  • DNA writing and reading in the cell
  • Evolution control

2009-03-30

Project options were further narrowed down to the following 3 fields.

  • Light sensor
  • Cell density control
  • DNA recombination