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Team:Alberta/References/Publications/Compilation and analysis of Escherichia coli promoter DNA sequences
From 2009.igem.org
Diane K.Hawley and William R.McClure
Nucleic Acids Research, 1983, Vol. 11, No. 8 2237-2255
Abstract: The DNA sequence of 168 promoter regions (-50 to +10) for Escherichia
coli RNA polymerase were compiled. The complete listing was divided into
two groups depending upon whether or not the promoter had been defined by
genetic (promoter mutations) or biochemical (5' end determination)
criteria. A consensus promoter sequence based on homologies among 112
well-defined promoters was determined that was in substantial agreement
with previous compilations. In addition, we have tabulated 98 promoter
mutations. Nearly all of the altered base pairs in the mutants conform to
the following general rule: down-mutations decrease homology and
up-mutations increase homology to the consensus sequence.
Link: Nucleic Acids Research
