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Team:BCCS-Bristol/Modeling/Growth Rate
From 2009.igem.org
Growth Rate of the Bacterium
It has been shown that the growth rate of single bacteria is a trilinear function. Click [http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B94RW-4TX32HC-12-17&_cdi=56421&_user=121739&_coverDate=01%2F31%2F2008&_sk=%23TOC%2356421%232008%23999059998%23701858%23FLA%23display%23Volume_94,_Issue_1,_Pages_L01-L03,_1-330_(January_2008)%23tagged%23Volume%23first%3D94%23Issue%23first%3D1%23date%23(January_2008)%23&view=c&_gw=y&wchp=dGLzVtb-zSkzV&md5=cc8273c507689afe9c4c635da517b404&ie=/sdarticle.pdf here] for a link to the paper.
This means that the growth of the bacterium can be divided into 3 phases.
- Phase 1
- From time zero, T_0, to the time when formation of the septum begins, T_c.
- Phase 2
- From the time when formation of the septum begins, T_c, to the time T_2.
- Phase 3
- From the time T_2 to the generation time, T_g.
At each phase there is an individual linear growth rate, or gradient, a. Values for the parameters are shown in the table below:
| Parameter * | Mean | S.D. |
| a_1 | 0.067 | 0.027 |
| a_2 | 0.122 | 0.035 |
| a_3 | 0.174 | 0.049 |
| T_c | 11.42 | 6.78 |
| T_2 | 21.15 | 6.02 |
| T_g | 25.08 | 7.97 |
* Times are in minutes and growth rates are in micrometres/minute.
