Team:Imperial College London/Thermoinduction

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(Module Integration - Thermoinduction)
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==The thermoinducible system==
==The thermoinducible system==
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[[Image:Ii09 thermo.png|300px]]<br>
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The lambda promoter is strongly repressed at 28 degrees by the cI repressor.  Therefore, at 28 degrees, the thermoinducible system has no activity. <br>
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The
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However, this cI repressor is unique in that it is temperature-sensitive, and will readily lose its functional structure as the temperature increases.  Therefore, when the temperature is raised to 42 degrees, the lambda promoter is no longer repressed and can trigger module 3. <br>
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<html><a href="https://2009.igem.org/Team:Imperial_College_London/Temporal_Control/Thermoinduction"><img style="vertical-align:bottom;" width=50px align="left" src="http://i691.photobucket.com/albums/vv271/dk806/II09Learnmore.png"></a></html>&nbsp; <b><i>About Thermoinduction.</i></b>
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==Results==
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Revision as of 21:31, 18 October 2009

Module Integration - Thermoinduction




After encapsulation, it becomes more difficult for normal chemical induction to penetrate the outer protective coating. To tackle this problem, heat induction is used. The temperature is raised to 42 degrees, which activates a thermoinducible promoter system and consequently starts module 3.

The thermoinducible system

Ii09 thermo.png

The lambda promoter is strongly repressed at 28 degrees by the cI repressor. Therefore, at 28 degrees, the thermoinducible system has no activity.

However, this cI repressor is unique in that it is temperature-sensitive, and will readily lose its functional structure as the temperature increases. Therefore, when the temperature is raised to 42 degrees, the lambda promoter is no longer repressed and can trigger module 3.

  About Thermoinduction.

Results




Mr. Gene   Geneart   Clontech   Giant Microbes