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Team:Virginia Commonwealth/Overview
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| + | ==Motivation== | ||
| + | The rational, forward engineering of genetically-encoded biological systems relies partly on 1) the generation of a multitude of genetic parts and 2) the sufficient characterization of these parts. This project aims to contribute to the advancement of synthetic biology by 1) generating and sharing a library of transcriptional enhancers called UP-elements (a new class of BioBrick parts), 2) characterizing strength of transcription initiation by measuring both mRNA and protein levels (by RT-PCR and flow cytometry, respectively) and 3) elucidating UP-element design principles. We hope that the results of this project will be useful to the community. | ||
| + | ==Safety== | ||
| + | #The nature of this project does not raise any unusual safety concerns. | ||
| + | #The local biosafety committee is the VCU School of Engineering Safety Committee. | ||
| + | #One of our advisors, Cindy Lovelace, serves on the committee and makes sure that our team followed all safety guidelines. | ||
| + | #Our new BioBrick parts should not raise any unusual safety concerns. | ||
| + | ==Background== | ||
Background papers related to synthetic biology | Background papers related to synthetic biology | ||
*[[Team:Virginia_Commonwealth/Literature| Papers]] | *[[Team:Virginia_Commonwealth/Literature| Papers]] | ||
Revision as of 14:48, 21 October 2009
Motivation
The rational, forward engineering of genetically-encoded biological systems relies partly on 1) the generation of a multitude of genetic parts and 2) the sufficient characterization of these parts. This project aims to contribute to the advancement of synthetic biology by 1) generating and sharing a library of transcriptional enhancers called UP-elements (a new class of BioBrick parts), 2) characterizing strength of transcription initiation by measuring both mRNA and protein levels (by RT-PCR and flow cytometry, respectively) and 3) elucidating UP-element design principles. We hope that the results of this project will be useful to the community.
Safety
- The nature of this project does not raise any unusual safety concerns.
- The local biosafety committee is the VCU School of Engineering Safety Committee.
- One of our advisors, Cindy Lovelace, serves on the committee and makes sure that our team followed all safety guidelines.
- Our new BioBrick parts should not raise any unusual safety concerns.
Background
Background papers related to synthetic biology
