Team:Heidelberg

From 2009.igem.org

(Difference between revisions)
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__NOTOC__
<html>
<html>
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 +
 +
<style>
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h1.firstHeading { display: none; }
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p {text-align: justify;}
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a:link { color: #00b0e6; text-decoration: none}
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a:visited { color:#00b0e6; text-decoration: none}
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a:hover { color:#f29400; text-decoration: none}
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a:active { color:#f29400; text-decoration: none}
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#bodyContent { padding: 10px auto; width: 910px; margin: auto; clear: none; }
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table#team_members { text-align: justify; border: 0; }
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table#team_members h2, table#team_members h3 { clear: both; }
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/*-----------------------------------------------------------------------------------------------*/
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div.MenuBar ul li ul.DropDownMenu {
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  display: none; /* Hides all drop-down menus. */
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}
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/*
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li:hover works in IE7 and FF2.
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a:hover works in IE6 and FF2.
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a:hover breaks li:hover in FF2.
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*/
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div.MenuBar ul li:hover ul.DropDownMenu li ul.SideMenu,
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div.MenuBar ul li a:hover ul.DropDownMenu li a ul.SideMenu {
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  display: none; /* Hides all side menus. */
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}
 +
/*------------------------------------------------------------------------------------- Menu Bar */
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div.MenuBar {
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  font: arial, helvetica, sans-serif;
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  height: 30px;
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  width: 910px;
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  /*width: 100%*/
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  margin: 0;
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  border-top: 0;
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  border-right: 0;
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  border-left: 0;
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  padding: 0;
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  background: black;
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}
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div.MenuBar ul {
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  font: arial, helvetica, sans-serif;
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  text-align: center;
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  list-style-type: none;
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  margin: 0.5em auto;
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  border: 0;
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  padding: 0;
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  background: black;
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}
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div.MenuBar ul li {
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  font: arial, helvetica, sans-serif;
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  display: block;
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  padding: 0;
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  margin: 0;
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  font-size: 1.3em;
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  float: left;
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  background: black;
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  text-align: center;
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  width: 107px;
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  position: relative; /* Sets the positioning context for each drop-down menu. */
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}
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div.MenuBar ul li a {
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  font: arial, helvetica, sans-serif;
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  display: block;
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  background: black;
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  height: 22px; /* Keep height + padding-top + padding-bottom sync with the menu bar height. */
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  color: #ffffff;
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  padding-top: 4px;
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  padding-bottom: 4px;
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  padding-left: 1em; /* Sets the left space between top-level items. */
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  padding-right: 1em; /* Sets the right space between top-level items. */
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  text-decoration: none;
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}
 +
 +
/*------------------------------------------------------------------------------ Drop-Down Menus */
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div.MenuBar ul li:hover ul.DropDownMenu,
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div.MenuBar ul li a:hover ul.DropDownMenu {
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  display: block;
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  width: 10em; /* Drop-down menu width.
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                  Use MenuTailor.css to customize. */
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  height: 1em;
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  padding: 1px; /* Sets the drop-down menu "effective border" width. */
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  position: absolute;
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  top: 23px; /* Places the drop-down menu under the menu bar.
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                Keep it sync with the menu bar height. */
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  left: 0; /* Aligns the drop-down menu to its top-level item. */
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  background-color: black; /* Selected item. */
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  color: #FFFFFF;
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}
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div.MenuBar ul li:hover ul.DropDownMenu li a,
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div.MenuBar ul li a:hover ul.DropDownMenu li a {
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  width: 10em; /* Keep it sync with the drop-down menu width.
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                            Use MenuTailor.css to customize. */
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  height: 1em;
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  padding-left: 0;
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  padding-right: 0;
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  background-color: black; /* Selected item. */
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  color: #FFFFFF;
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}
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ul.DropDownMenu li a span {
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  display: block;
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  padding-left: 0.75em; /* Sets the left space of each drop-down menu item. */
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  padding-right: 0.25em; /* Sets the right space of each drop-down menu item. */
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  text-align: right; /* Aligns the >> symbol to the right. */
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}
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ul.DropDownMenu li a span span {
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  float: left; /* Aligns the text (back) to the left. */
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  font: 12px arial, helvetica, sans-serif; /* Required for IE55. */
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  height: 20px;
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  color: #FFFFFF;
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}
 +
/*----------------------------------------------------------------------------------- Side Menus */
 +
div.MenuBar ul li:hover ul.DropDownMenu li:hover ul.SideMenu,
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div.MenuBar ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu {
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  display: block;
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  width: 11em; /* Side menu width.
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                  Use MenuTailor.css to customize. */
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  padding: 1px; /* Sets the side menu "effective border" width. */
 +
  position: absolute;
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  top: -1px; /* Aligns the side menu to its drop-down menu item.
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                Keep it sync with the side menu "effective border" width. */
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  left: 13em; /* Places the side menu to the right of the drop-down menu.
 +
                            Keep it sync with the drop-down menu width.
 +
                            Use MenuTailor.css to customize. */
 +
}
 +
div.MenuBar ul li:hover ul.DropDownMenu li:hover ul.SideMenu li a,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu li a {
 +
  width: 11em; /* Keep it sync with the side menu width.
 +
                            Use MenuTailor.css to customize. */
 +
  font: 12px arial, helvetica, sans-serif; /* Required for IE55. */
 +
  left: 13em; /* Places the side menu to the right of the drop-down menu.
 +
                            Keep it sync with the drop-down menu width.
 +
                            Use MenuTailor.css to customize. */
 +
}
 +
div.MenuBar ul li ul.DropDownMenu li ul.SideMenu li a span {
 +
  padding-left: 1.5em; /* Sets the left space of each side menu item. */
 +
  padding-right: 0.5em; /* Sets the right space of each side menu item. */
 +
  text-align: left;
 +
  font: 12px arial, helvetica, sans-serif; /* Required for IE55. */
 +
  left: 13em; /* Places the side menu to the right of the drop-down menu.
 +
                            Keep it sync with the drop-down menu width.
 +
                            Use MenuTailor.css to customize. */
 +
}
 +
/*----------------------------------------------------------------------------- Browser Specific */
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* html div.MenuBar ul li a {
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  float: left; /* Required for IE55 and IE6.
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                            Breaks O9.
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                            Hidden (* html) from non-IE browsers. */
 +
}
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* html ul.DropDownMenu li a:hover {
 +
  cursor: hand; /* Required for IE55.
 +
                  Hidden (* html) from non-IE browsers. */
 +
}
 +
ul.DropDownMenu li a:hover {
 +
  cursor: pointer; /* Required for IE6 and IE7.
 +
                      Hidding it (* html) from non-IE browsers breaks IE7!
 +
}
 +
* html div.MenuBar a:hover {
 +
  text-decoration: none; /* Required for IE55 and IE6.
 +
                            Hidden (* html) from non-IE browsers. */
 +
}
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* html div.MenuBar ul li table,
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* html div.MenuBar ul li table td {
 +
  border: 0; /* Required for IE55 and IE6.
 +
                Hidden (* html) from non-IE browsers. */
 +
}
 +
/*------------------------------------------------------------------------------- Default Colors */
 +
div.MenuBar {
 +
  background-color: Menu;
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  border-bottom: 1px solid ButtonShadow;
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}
 +
div.MenuBar a {
 +
  background-color: Menu; /* Top-level unselected items. */
 +
  color: MenuText;
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}
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div.MenuBar ul li:hover a,
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div.MenuBar ul li a:hover {
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  color: #ea7f16;
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  background-color: Highlight; /* Top-level selected item. */
 +
  color: HighlightText;
 +
}
 +
/*...............................................................................................*/
 +
div.MenuBar ul li:hover ul.DropDownMenu,
 +
div.MenuBar ul li a:hover ul.DropDownMenu {
 +
  background-color: ButtonShadow; /* Sets the drop-down menu "effective border" color. */
 +
}
 +
div.MenuBar ul li:hover ul.DropDownMenu li a,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a {
 +
  background-color: Menu;  Drop-down menu unselected items.
 +
                            Sets the drop-down menu "effective background" color. */
 +
  color: MenuText;
 +
}
 +
div.MenuBar ul li:hover ul.DropDownMenu li:hover a,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a:hover {
 +
  background-color: Highlight; /* Drop-down menu selected item. */
 +
  color: HighlightText;
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}
 +
/*...............................................................................................*/
 +
div.MenuBar ul li:hover ul.DropDownMenu li:hover ul.SideMenu,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu {
 +
  background-color: ButtonShadow; /* Sets the side menu "effective border" color. */
 +
}
 +
div.MenuBar ul li:hover ul.DropDownMenu li:hover ul.SideMenu li a,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu li a {
 +
  background-color: Menu; /* Side menu unselected items.
 +
                            Sets the side menu "effective background" color. */
 +
  color: MenuText;
 +
}
 +
div.MenuBar ul li:hover ul.DropDownMenu li:hover ul.SideMenu li a:hover,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu li a:hover {
 +
  background-color: Highlight; /* Side menu selected item. */
 +
  color: HighlightText;
 +
}
 +
/*-----------------------------------------------------------------------------------------------*/
 +
/*Script-Free 3-Level Menu 1.2 Tailor
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  www.CesarDaniel.info
 +
/*-------------------------------------------------------------------------------------- General */
 +
body {
 +
  background: white;
 +
  color: black;
 +
  margin: 0;
 +
  border: 0;
 +
  padding: 0;
 +
}
 +
 +
 +
div.MenuBar {
 +
  font: 13px arial, helvetica, sans-serif;
 +
}
 +
div.MenuBar ul {
 +
  font: 13px arial, helvetica, sans-serif; /* Required for IE55. */
 +
}
 +
/*--------------------------------------------------------------------------------------- Colors */
 +
div.MenuBar {
 +
  background-color: black; /* Selected item. */
 +
  color: #FFFFFF;
 +
  border-bottom: 1px solid ButtonShadow;
 +
}
 +
div.MenuBar a,
 +
div.MenuBar ul li:hover ul.DropDownMenu li a,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a,
 +
div.MenuBar ul li:hover ul.DropDownMenu li:hover ul.SideMenu li a,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu li a {
 +
  background-color: black; /* Selected item. */
 +
  color: #FFFFFF;
 +
}
 +
div.MenuBar ul li:hover a,
 +
div.MenuBar ul li a:hover,
 +
div.MenuBar ul li:hover ul.DropDownMenu li:hover a,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a:hover,
 +
div.MenuBar ul li:hover ul.DropDownMenu li:hover ul.SideMenu li a:hover,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu li a:hover {
 +
  background-color: #00b0e6; /* Selected item. */
 +
  color: #FFFFFF;
 +
}
 +
div.MenuBar ul li:hover ul.DropDownMenu,
 +
div.MenuBar ul li a:hover ul.DropDownMenu,
 +
div.MenuBar ul li:hover ul.DropDownMenu li:hover ul.SideMenu,
 +
div.MenuBar ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu {
 +
  background-color: ButtonShadow; /* Sets the drop-down and side menus "effective border" color. */
 +
}
 +
/*--------------------------------------------------------------------------------------- Widths */
 +
/*
 +
 +
/*
 +
Menu Bar 1
 +
Drop-Down Menu #2
 +
*/
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu#MB1-DDM4,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu#MB1-DDM4,
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu#MB1-DDM4 li a,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu#MB1-DDM4 li a {
 +
  width: 11em; /* Drop-down menu width. */
 +
}
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu#MB1-DDM5,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu#MB1-DDM5,
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu#MB1-DDM5 li a,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu#MB1-DDM5 li a {
 +
  width: 12em; /* Drop-down menu width. */
 +
}
 +
 +
/*...............................................................................................*/
 +
/*
 +
Menu Bar 1
 +
Drop-Down Menu #2
 +
Side Menu #1
 +
*/
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM1,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu#MB1-DDM2-SM1 {
 +
  left: 15.5em !important; /* Places the side menu to the right of the drop-down menu.
 +
                            Keep it sync with the drop-down menu width. */
 +
}
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM1,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu#MB1-DDM2-SM1,
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM1 li a,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu#MB1-DDM2-SM1 li a {
 +
  width: 10em; /* Side menu width. */
 +
}
 +
/*...............................................................................................*/
 +
/*
 +
Menu Bar 1
 +
Drop-Down Menu #2
 +
Side Menu #2
 +
*/
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM2,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu#MB1-DDM2-SM2 {
 +
  left: 15.5em  !important; /* Places the side menu to the right of the drop-down menu.
 +
                            Keep it sync with the drop-down menu width. */
 +
}
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM2,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu#MB1-DDM2-SM2,
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM2 li a,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu#MB1-DDM2-SM2 li a {
 +
  width: 10em; /* Side menu width. */
 +
}
 +
/*...............................................................................................*/
 +
/*
 +
Menu Bar 1
 +
Drop-Down Menu #2
 +
Side Menu #3
 +
*/
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM3,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu#MB1-DDM2-SM3 {
 +
  left: 15.5em  !important; /* Places the side menu to the right of the drop-down menu.
 +
                            Keep it sync with the drop-down menu width. */
 +
}
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM3,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu#MB1-DDM2-SM3,
 +
div.MenuBar#navi ul li:hover ul.DropDownMenu li:hover ul.SideMenu#MB1-DDM2-SM3 li a,
 +
div.MenuBar#navi ul li a:hover ul.DropDownMenu li a:hover ul.SideMenu#MB1-DDM2-SM3 li a {
 +
  width: 10em; /* Side menu width. */
 +
}
 +
/*...............................................................................................*/
 +
 +
</style>
 +
 +
 +
<body>
 +
<div id="header"><img src="https://static.igem.org/mediawiki/2008/7/78/TeamHeidelbergHeader.jpg" alt="Team Heidelberg" /></div>
 +
<div class='MenuBar' id="navi">
 +
<ul>
 +
<li>
 +
<a href="https://2008.igem.org/Team:Heidelberg" style="color: white">Home
 +
<!--[if gt IE 6]><!--></a><!--<![endif]-->
 +
<!--[if lt IE 7]><table border="0" cellpadding="0" cellspacing="0"><tr><td><![endif]-->
 +
<!--[if lte IE 6]></td></tr></table></a><![endif]-->
 +
</li>
 +
<li>
 +
<a href="https://2008.igem.org/Team:Heidelberg/Team" style="color: white">Team<!--[if gt IE 6]><!--></a><!--<![endif]-->
 +
<!--[if lt IE 7]><table border="0" cellpadding="0" cellspacing="0"><tr><td><![endif]-->
 +
<ul class="DropDownMenu" id="MB1-DDM6">
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Team"><span><span>Overview</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Team_Members#Advisors"><span><span>Advisors</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Team_Members#Undergraduates"><span><span>Undergraduates</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Team#There_are_many_Universities_-_and_there_is_Heidelberg_..."><span><span>University</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Team#DKFZ"><span><span>DKFZ</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Team#Bioquant"><span><span>BioQuant</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/BioRegioRN"><span><span>BioRegion Rhein-Neckar</span></span></a></li>
 +
</ul>
 +
<!--[if lte IE 6]></td></tr></table></a><![endif]-->
 +
</li>
 +
<li>
 +
<a href="https://2008.igem.org/Team:Heidelberg/Project" style="color: white">Project<!--[if gt IE 6]><!--></a><!--<![endif]-->
 +
<!--[if lt IE 7]><table border="0" cellpadding="0" cellspacing="0"><tr><td><![endif]-->
 +
<ul class="DropDownMenu" id="MB1-DDM1">
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Project"><span><span>Overall Project</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Notebook/material"><span><span>Material & Methods</span></span></a>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Project/Sensing"><span><span>Sensing</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Project/Killing_I"><span><span>Killing I  - Phages</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Project/Killing_II"><span><span>Killing II - Colicin</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Project/Visualization"><span><span>Visualization</span></span></a></li>
 +
</ul>
 +
<!--[if lte IE 6]></td></tr></table></a><![endif]-->
 +
</li>
 +
 +
<li>
 +
<a href="https://2008.igem.org/Team:Heidelberg/Parts" style="color: white">Parts<!--[if gt IE 6]><!--></a><!--<![endif]-->
 +
<!--[if lt IE 7]><table border="0" cellpadding="0" cellspacing="0"><tr><td><![endif]-->
 +
<ul class="DropDownMenu" id="MB1-DDM2">
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Parts"><span><span>Submitted Parts</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Parts/Characterization"><span><span>Characterization</span></span></a></li>
 +
</ul>
 +
<!--[if lte IE 6]></td></tr></table></a><![endif]-->
 +
</li>
 +
<li>
 +
<a href="https://2008.igem.org/Team:Heidelberg/Modeling" style="color: white">Modeling<!--[if gt IE 6]><!--></a><!--<![endif]-->
 +
<!--[if lt IE 7]><table border="0" cellpadding="0" cellspacing="0"><tr><td><![endif]-->
 +
<ul class="DropDownMenu" id="MB1-DDM3">
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Modeling"><span><span>Overview</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Modeling/Chemotaxis"><span><span>Chemotaxis-Colicin</span></span></a></li>
 +
<li><a href="https://2008.igem.org/Team:Heidelberg/Modeling/Phage"><span><span>Phage Dynamics model</span></span></a></li>
 +
</ul>
 +
<!--[if lte IE 6]></td></tr></table></a><![endif]-->
 +
</li>
 +
<li>
 +
<a href="https://2008.igem.org/Team:Heidelberg/Notebook/Overview" style="color: white">Notebook<!--[if gt IE 6]><!--></a><!--<![endif]-->
 +
<!--[if lt IE 7]><table border="0" cellpadding="0" cellspacing="0"><tr><td><![endif]-->
 +
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==Available Languages==
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[[Image:british_flag.jpg|middle|15px]] [[Team:Heidelberg#Bacterial killers from a genetic construction kit|English]]        [[Image:German_flag_c.jpg|middle|15px]] [[Team:Heidelberg#Bakterienkiller aus dem Gen-Baukasten|Deutsch]]        [[Image:French_flag.jpg‎|middle|15px]] [[Team:Heidelberg#assasins bakterielles d'un kit construction|Français]]        [[Image:Italian_flag.jpg|middle|15px]] [[Team:Heidelberg#Un kit genetico per batteri killer|Italiano]]        [[Image:Spanish_flag.jpg|middle|15px]] [[Team:Heidelberg#Bacterias matadoras creadas a partir de un kit de construcción genética|Español]]        [[Image:Portugese_flag.jpg|middle|15px]] [[Team:Heidelberg#Bactérias predadoras a partir de um kit deconstrução genética|Português]]        [[Image:Catalonia_flag.jpg|middle|15px]] [[Team:Heidelberg#Bacteries assassines generades a partir d’ un kit de construcció genètica|Català]]        [[Image:Poland_flag.jpg|middle|15px]] [[Team:Heidelberg#Bakteryjni zabójcy z taśmy montażowej|Polski]]        [[Image:Lithuanin_flag.jpg|middle|15px]] [[Team:Heidelberg#Genetiškai sukonstruoti bakterijų žudikai|Lietuvių]]
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[[Image:Russian_flag.jpg|middle|15px]] [[Team:Heidelberg#Ликвидатор бактерий созданный из генетических материалов|Pусский]]        [[Image:China_flag.jpg|middle|15px]] [[Team:Heidelberg#由基因元件拼装的细菌杀手|中文]]        [[Image:Japanese_flag.jpg|middle|15px]] [[Team:Heidelberg#殺し屋のバクテリアを遺伝子コンストラクトキットで作る|日本語]]
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=='''Bacterial killers from a genetic construction kit'''==
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<div>
<div>
==Project abstract==
==Project abstract==

Revision as of 17:43, 16 July 2009

Available Languages

15px English 15px Deutsch 15px Français 15px Italiano 15px Español 15px Português 15px Català 15px Polski 15px Lietuvių

15px Pусский 15px 中文 15px 日本語

Bacterial killers from a genetic construction kit

Project abstract

Early efforts in synthetic biology have focused on using prokaryotes as an engineering chassis, whereas novel developments indicate a shift towards an eukaryotic synthetic biology. The value of eukaryotic synthetic biology is manifold: in medical research, it will accomplish new ways of gene therapy; in plant biotechnology, it can contribute to the struggle for a sustainable food and energy solution. Finally, the ability to assemble and analyze complicated biological systems step by step will allow a revolutionary approach to fundamental research. Establishing new standards for iGEM, the Heidelberg 2009 team will be concerned with developing ways for measuring promoters in mammalian cells, a default chassis and a first evaluation of the recently postulated BioBrick beta proposal 2 (Tom Knight). Considering the importance of controlling gene expression, our team's work will focus on natural and synthetic mammalian promoters. Our vision is to provide the synthetic biology community with a methodical library of such promoters (with different output strength and sensitivity to different regulatory proteins) and a model which can provide guidance for the development of further synthetic promoters. Our efforts will therefore, from the very beginning, equally entail bioinformatics and wet lab work. As an early application for such a promoter library, our team will attempt to develop an assay which can monitor the activity of several pathways in one cell. Such an assay is of high value for biological research as it can be applied for studying stem cell differentiation, tumor formation, apoptosis and autophagy as well as drug response. Our team will apply the assay towards testing several anti-cancer drugs. A computer-based model will lay the foundations for future work. It will help us to build a logic that integrates the promoter activities and will

allow us to predict the possibilities of a single functional output.

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