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where k<sub>on</sub> describes the collisions of X and D that occur per time per protein at a given concentration and k<sub>off</sub> determines the strength of the chemical binding X and D. In form of a differential equation, the rate of change of [XD] is described by | where k<sub>on</sub> describes the collisions of X and D that occur per time per protein at a given concentration and k<sub>off</sub> determines the strength of the chemical binding X and D. In form of a differential equation, the rate of change of [XD] is described by | ||
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Revision as of 11:47, 14 August 2009
University of Aberdeen - Pico Plumber
iGEM 2009
Repression of a Promoter
During repression of a promoter a repressor protein, X, binds to a DNA site of the promoter, D. The product of this binding process is [XD]. [XD] can also fall apart into [X] and [D] again:
(I)
where kon describes the collisions of X and D that occur per time per protein at a given concentration and koff determines the strength of the chemical binding X and D. In form of a differential equation, the rate of change of [XD] is described by
(II)
