Team:Imperial College London/Drylab/Autoinduction

From 2009.igem.org

(Difference between revisions)
(Model 1)
Line 30: Line 30:
[1]Kompala, D.S., D. Ramkrishna and G.T. Tsao, "Cybernetic modeling of microbial growth on multiple substrates," Biotechnology and Bioengineering 26 :1272-1281 (1984). <br>
[1]Kompala, D.S., D. Ramkrishna and G.T. Tsao, "Cybernetic modeling of microbial growth on multiple substrates," Biotechnology and Bioengineering 26 :1272-1281 (1984). <br>
[2] Zhao Lu et al. "Dynamics of Glucose-Lactose Diauxic Growth in E.coli". arXiv:0708.1993v1 [q-bio.OT] 15 Aug 2007
[2] Zhao Lu et al. "Dynamics of Glucose-Lactose Diauxic Growth in E.coli". arXiv:0708.1993v1 [q-bio.OT] 15 Aug 2007
 +
<br><br>
 +
<html><center><a href="https://2009.igem.org/Team:Imperial_College_London/Drylab/Autoinduction"><img style="vertical-align:bottom;" width="20%" src="http://i691.photobucket.com/albums/vv271/dk806/II09_Drylabmainimage1.png"></a><a href="https://2009.igem.org/Team:Imperial_College_London/Drylab/Protein_Production"><img style="vertical-align:bottom;" width="20%" src="http://i691.photobucket.com/albums/vv271/dk806/II09_Drylabmainimage2.png"></a><a href="https://2009.igem.org/Team:Imperial_College_London/Drylab/Enzyme"><img style="vertical-align:bottom;" width="20%" src="http://i691.photobucket.com/albums/vv271/dk806/II09_Drylabmainimage3.png"></a>
 +
<a href="https://2009.igem.org/Team:Imperial_College_London/Drylab/Genome_deletion"><img style="vertical-align:bottom;" width="20%" src="http://i691.photobucket.com/albums/vv271/dk806/II09_Drylabmainimage5.png"></a></center></html>
 +
 +
<html><table border="0" style="background-color:transparent;" width="100%">
 +
<tr><td width="0%">&nbsp;</td>
 +
<td width="22%"><center><a href="https://2009.igem.org/Team:Imperial_College_London/Drylab/Autoinduction"><b>Autoinduction</b></a></center></td>
 +
<td width="22%"><center><a href="https://2009.igem.org/Team:Imperial_College_London/Drylab/Protein_Production"><b>Protein Production</b></a></center></td>
 +
<td width="22%"><center><a href="https://2009.igem.org/Team:Imperial_College_London/Drylab/Enzyme"><b>Drug Kinetics</b></a></center></td>
 +
<td width="22%"><center><a href="https://2009.igem.org/Team:Imperial_College_London/Drylab/Genome_deletion"><b>Genome Deletion</b></a></center></td>
 +
<td width="1%"></td>
 +
</tr></table></html>
 +
<br>
 +
<!--
<!--

Revision as of 15:28, 8 October 2009




Autoinduction

II09 diauxi illust.jpg

Starting the encapsulation process is related to diauxic growth of bacteria under two carbon sources. This is explained further here. 2 models have been discussed in this section and more information about each can be found in the tabs.

Contents

Goal of the models

  • Provide understanding of the [http://en.wikipedia.org/wiki/Diauxie diauxic growth] phenomenon
  • Find out the time taken to consume glucose in the medium to characterize the CRP promoter.

Model 1

  • This is a cybernetic model developed by Kompala et al [1].
  • It is based on Michaelis-Menten assumptions for substrate consumption.

Model 2

Details coming up soon! Still running long simulations...

References

[1]Kompala, D.S., D. Ramkrishna and G.T. Tsao, "Cybernetic modeling of microbial growth on multiple substrates," Biotechnology and Bioengineering 26 :1272-1281 (1984).
[2] Zhao Lu et al. "Dynamics of Glucose-Lactose Diauxic Growth in E.coli". arXiv:0708.1993v1 [q-bio.OT] 15 Aug 2007

 
Autoinduction
Protein Production
Drug Kinetics
Genome Deletion


Mr. Gene   Geneart   Clontech   Giant Microbes