Team:NTU-Singapore/Notebook/Brainstorming

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Latest revision as of 01:38, 22 October 2009

Welcome to the notebook page!

Brainstorming Ideas

Health & medicine

Create an insulin delivery system which response to low glucose level or time controlled release

Vitamin synthesis?

Hinder carcinogenics
- Maslinic acid (olive skin)-tritrepenoid compound
- Can we study anti-tumoral and apoptotic effect of this compound?
- E coli to interfere in the carcinogenic pathways
- Mimic the maslinic effect to the carcinogenic cells?
- Surface markers?

Trap parasites in host cells by disabling the protease
- Can we remove the trap parasites?
- Terminate parasites?

Genetic modified bacteria that have anticoagulant properties.

Eczema relief

Bacteria to treat gangrene
- To eat up dead tissues
- Bacteria to deliver growth factors

Collagen producing bacteria

Bacteria that absorbs cholesterol

Constipation pill

Synthesis specific growth factors

Bacteria that produce PDGF

Using bacteria to breakdown blockage in blood vessels

Malaria vaccine
- Forcibly expresses a certain gene and create a vaccine against it
- Proof of concept

Cancer treatment - colon cancer(CA marker)
- Fusion protein to signal the expression of perforin (e coli as NKC)

Streptococcus vaccine

p-Falciparum gene expression stabilization for malaria

Intestinal vaccine delivery

Bacteria to target the larvae

To separate Tamoxifen (possibly a chiral drug) by uptake the drugs into modified E Coli and bind it to the receptor inside the bacteria.

Biosensor

Biosensor that sense the present of allergen and release drugs to prevent allergenic response

Mimic allergy response-to determine allergen?

Fingerprint detection

Can cells response to magnetic fields?
- Bird GPS ??
- Magnetic field biosensor

Biosensor to detect cancer

Environmental

E coli to detect toxins in food and flu strain in animals.

Biomask
- For absorption

Create a water purifying system that recognize and trap toxic
- to uptake salt and others- sea water purification

Bacteria producing water for the use of photosynthesis so that plants can grow well in dry area
- Is it possible to construct water using certain metabolism pathway?

Signalling

Multi-color display according to inputs
- to improve signal inputs
DNA methylation as memory storage
suffocate the cells
baccine
To construct guiding E Coli that guide pathogenic bacteria to a region of toxin/UV light.

Application

bacterial barometer
fill up crack
dust repel
microscopic spring-using spirobac
To construct a Sound sensing bacteria

Modeling

modeling the trend of evolution of flu viruses

Bioproduction

Methanol in E-coli

Navigation

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iGEM '09 || TOP

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 <div class="grid_11 prefix_1 suffix_1" id="note">
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 * Create an insulin delivery system which response to low glucose level or time controlled release
 * Vitamin synthesis?
 * Hinder carcinogenics
 ** Maslinic acid (olive skin)-tritrepenoid compound
 ** Can we study anti-tumoral and apoptotic effect of this compound?
 ** E coli to interfere in the carcinogenic pathways
-** mimic the maslinic effect to the carcinogenic cells?
+** Mimic the maslinic effect to the carcinogenic cells?
-** surface markers?
+** Surface markers?
+* Trap parasites in host cells by disabling the protease
+** Can we remove the trap parasites?
+** Terminate parasites?
+* Genetic modified bacteria that have anticoagulant properties.
+* Eczema relief
+* Bacteria to treat gangrene
+** To eat up dead tissues
+** Bacteria to deliver growth factors
+* Collagen producing bacteria
+* Bacteria that absorbs cholesterol
+* Constipation pill
+* Synthesis specific growth factors
+* Bacteria that produce PDGF
+* Using bacteria to breakdown blockage in blood vessels
+* Malaria vaccine
+** Forcibly expresses a certain gene and create a vaccine against it
+** Proof of concept
+*  Cancer treatment - colon cancer(CA marker)
+** Fusion protein to signal the expression of perforin (e coli as NKC)
+* Streptococcus vaccine
+* p-Falciparum gene expression stabilization for malaria
+* Intestinal vaccine delivery
+* Bacteria to target the larvae
+*To separate Tamoxifen (possibly a chiral drug) by uptake the drugs into modified E Coli and bind it to the receptor inside the bacteria.
+== Biosensor ==
+* Biosensor that sense the present of allergen and release drugs to prevent allergenic response
+* Mimic allergy response-to determine allergen?
+* Fingerprint detection
+* Can cells response to magnetic fields?
+** Bird GPS ??
+** Magnetic field biosensor
+* Biosensor to detect cancer
+== Environmental ==
+* E coli to detect toxins in food and flu strain in animals.
+* Biomask
+** For absorption
+* Create a water purifying system that recognize and trap toxic
+** to uptake salt and others- sea water purification
+* Bacteria producing water for the use of photosynthesis so that plants can grow well in dry area
+** Is it possible to construct water using certain metabolism pathway?
+== Signalling ==
+* Multi-color display according to inputs
+** to improve signal inputs
+* DNA methylation as memory storage
+* suffocate the cells
+* baccine
+* To construct guiding E Coli that guide pathogenic bacteria to a region of toxin/UV light.
+==Application ==
+* bacterial barometer
+* fill up crack
+* dust repel
+* microscopic spring-using spirobac
+* To construct a Sound sensing bacteria
+==Modeling==
+* modeling the trend of evolution of flu viruses
+==Bioproduction==
+* Methanol in E-coli