Team:NTU-Singapore/Notebook/Brainstorming

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<div class="grid_11 prefix_1 suffix_1" id="note">
<div class="grid_11 prefix_1 suffix_1" id="note">
-
<span class="title">Experiment <span class="bold">Timeline</span></span>
+
<span class="title">Brainstorming <span class="bold">Ideas</span></span>
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* Create an insulin delivery system which response to low glucose level or time controlled release
* Create an insulin delivery system which response to low glucose level or time controlled release
 +
 +
* Vitamin synthesis?
* Vitamin synthesis?
 +
 +
* Hinder carcinogenics
* Hinder carcinogenics
** Maslinic acid (olive skin)-tritrepenoid compound
** Maslinic acid (olive skin)-tritrepenoid compound
** Can we study anti-tumoral and apoptotic effect of this compound?
** Can we study anti-tumoral and apoptotic effect of this compound?
** E coli to interfere in the carcinogenic pathways
** E coli to interfere in the carcinogenic pathways
-
** mimic the maslinic effect to the carcinogenic cells?
+
** Mimic the maslinic effect to the carcinogenic cells?
-
** surface markers?
+
** Surface markers?
-
* trap parasites in host cells by disabling the protease
+
 
 +
 
 +
* Trap parasites in host cells by disabling the protease
** Can we remove the trap parasites?
** Can we remove the trap parasites?
** Terminate parasites?
** Terminate parasites?
-
* genetic modified bacteria that have anticoagulant properties.
+
 
-
* eczema relief
+
 
-
* bacteria to treat gangrene
+
* Genetic modified bacteria that have anticoagulant properties.
-
** to eat up dead tissues
+
 
-
** bac to deliver growth factors
+
 
-
* collagen producing bacteria
+
* Eczema relief
-
* bacteria that absorbs cholesterol
+
 
-
* constipation pill
+
 
-
* synthesis specific growth factors
+
* Bacteria to treat gangrene
-
* bacteria tt produce PDGF
+
** To eat up dead tissues
-
* using bacteria to breakdown blockage in blood vessels
+
** Bacteria to deliver growth factors
-
* malaria vaccine
+
 
-
** forcibly experesses a certain gene and create a vaccine against it
+
 
-
** to prove the concept
+
* Collagen producing bacteria
-
*  cancer treatment-colon cancer(CA marker)
+
 
-
** fusion protein to signal the expression of perforin (e coli as NKC)
+
 
-
* streptococcus vaccine
+
* Bacteria that absorbs cholesterol
-
* p-falciparum gene expression stabilization ; Malaria
+
 
-
* intestinal vaccine delivery
+
 
-
* bac to target the larvae; Malaria
+
* Constipation pill
 +
 
 +
 
 +
* Synthesis specific growth factors
 +
 
 +
 
 +
* Bacteria that produce PDGF
 +
 
 +
 
 +
* Using bacteria to breakdown blockage in blood vessels
 +
 
 +
 
 +
* Malaria vaccine
 +
** Forcibly expresses a certain gene and create a vaccine against it
 +
** Proof of concept
 +
 
 +
 +
*  Cancer treatment - colon cancer(CA marker)
 +
** Fusion protein to signal the expression of perforin (e coli as NKC)
 +
 
 +
 
 +
* Streptococcus vaccine
 +
 
 +
 
 +
* p-Falciparum gene expression stabilization for malaria
 +
 
 +
 
 +
* Intestinal vaccine delivery
 +
 +
 
 +
* Bacteria to target the larvae
 +
 
 +
 
*To separate Tamoxifen (possibly a chiral drug) by uptake the drugs into modified E Coli and bind it to the receptor inside the bacteria.
*To separate Tamoxifen (possibly a chiral drug) by uptake the drugs into modified E Coli and bind it to the receptor inside the bacteria.
 +
== Biosensor ==
== Biosensor ==
-
* biosensor that sense the present of allergen and release drugs to prevent allergenic response
+
* Biosensor that sense the present of allergen and release drugs to prevent allergenic response
 +
 
 +
 
* Mimic allergy response-to determine allergen?
* Mimic allergy response-to determine allergen?
-
* fingerprint detection
+
 
 +
 
 +
* Fingerprint detection
 +
 
 +
 
* Can cells response to magnetic fields?
* Can cells response to magnetic fields?
** Bird GPS ??
** Bird GPS ??
-
** magnetic field biosensor
+
** Magnetic field biosensor
-
* biosensor to detect cancer
+
 
 +
 
 +
* Biosensor to detect cancer
 +
 
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* E coli to detect toxins in food and flu strain in animals.
* E coli to detect toxins in food and flu strain in animals.
 +
 +
* Biomask
* Biomask
** For absorption
** For absorption
-
* create a water purifying system that recognize and trap toxic
+
 
 +
 
 +
* Create a water purifying system that recognize and trap toxic
** to uptake salt and others- sea water purification
** to uptake salt and others- sea water purification
-
* bacteria producing water for the use of photosynthesis so that plants can grow well in dry area
+
 
-
** is it possible to construct water using certain metabolism pathway?
+
 
 +
* Bacteria producing water for the use of photosynthesis so that plants can grow well in dry area
 +
** Is it possible to construct water using certain metabolism pathway?
 +
 

Latest revision as of 01:38, 22 October 2009

Brainstorming Ideas


Health & medicine

  • Create an insulin delivery system which response to low glucose level or time controlled release


  • Vitamin synthesis?


  • Hinder carcinogenics
    • Maslinic acid (olive skin)-tritrepenoid compound
    • Can we study anti-tumoral and apoptotic effect of this compound?
    • E coli to interfere in the carcinogenic pathways
    • Mimic the maslinic effect to the carcinogenic cells?
    • Surface markers?


  •  Trap parasites in host cells by disabling the protease
    • Can we remove the trap parasites?
    • Terminate parasites?


  • Genetic modified bacteria that have anticoagulant properties.


  • Eczema relief


  • Bacteria to treat gangrene
    • To eat up dead tissues
    • Bacteria to deliver growth factors


  • Collagen producing bacteria


  • Bacteria that absorbs cholesterol


  • Constipation pill


  • Synthesis specific growth factors


  • Bacteria that produce PDGF


  • Using bacteria to breakdown blockage in blood vessels


  • Malaria vaccine
    •  Forcibly expresses a certain gene and create a vaccine against it
    • Proof of concept


  • Cancer treatment - colon cancer(CA marker)
    • Fusion protein to signal the expression of perforin (e coli as NKC)


  • Streptococcus vaccine


  • p-Falciparum gene expression stabilization for malaria


  • Intestinal vaccine delivery


  • Bacteria to target the larvae


  • To separate Tamoxifen (possibly a chiral drug) by uptake the drugs into modified E Coli and bind it to the receptor inside the bacteria.


Biosensor

  • Biosensor that sense the present of allergen and release drugs to prevent allergenic response


  • Mimic allergy response-to determine allergen?


  •  Fingerprint detection


  •  Can cells response to magnetic fields?
    • Bird GPS ??
    • Magnetic field biosensor


  •  Biosensor to detect cancer


Environmental

  • E coli to detect toxins in food and flu strain in animals.


  • Biomask
    •  For absorption


  • Create a water purifying system that recognize and trap toxic
    • to uptake salt and others- sea water purification


  • Bacteria producing water for the use of photosynthesis so that plants can grow well in dry area
    • Is it possible to construct water using certain metabolism pathway?


Signalling

  • Multi-color display according to inputs
    • to improve signal inputs
  • DNA methylation as memory storage
  • suffocate the cells
  • baccine
  • To construct guiding E Coli that guide pathogenic bacteria to a region of toxin/UV light.


Application

  • bacterial barometer
  • fill up crack
  • dust repel
  • microscopic spring-using spirobac
  • To construct a Sound sensing bacteria


Modeling

  • modeling the trend of evolution of flu viruses


Bioproduction

  • Methanol in E-coli





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