References
Introduction
- "Synthetic Biology. Applying Engineering to Biology". Report of a NEST High-Level Expert Group. European Commission, Directorate-General for Research. Available online at http://www.synbiosafe.eu/uploads///pdf/EU-highlevel-syntheticbiology.pdf
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- Voigt, C. Genetic parts to program bacteria. Current Opinion in Biotechnology 17 (5): 548–557 (2006).
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- Goodman, C. Engineering ingenuity at iGEM. Nat Chem Biology 4:13 (2008).
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- Venter M. Synthetic promoters: genetic control through cis engineering. Trends in Plant Science 12: 118-124 (2007). (and the references cited therein)
- Ogawa R. Construction of strong mammalian promoters by random cis-acting element elongation. Biotechniques 42: 628-632 (2007).
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Natural Promoters
- Alberts B., Johnson A., Walter P. & Lewis J. Molecular Biology of the Cell. 4th edition, 2008. Garland Science, Chapter 6, p. 357-359.
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Synthetic Promoters
- Alberts B., Johnson A., Walter P. & Lewis J. Molecular Biology of the Cell. 4th edition, 2008. Garland Science, p. 432-453
- Fussenegger M. & Weber, W. Engineering of Synthetic Mammalian Gene Networks. Chemistry and Biology 16: 287-297 (2009).
- Gossen M. & Bujard, L. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. PNAS 89: 5547-5551 (1992).
- Dorer D. E. & Nettelbeck, D. Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis. Advanced Drug Delivery Reviews 61: 554-557 (2009).
- Venter M. Synthetic promoters: genetic control through cis engineering. Trends in Plant Science 12: 118-124 (2007). (and the references cited therein)
- Rushton P. J., Reinstädler A., Lipka V., Lippok B. & Somssich I. E. Synthetic plant promoters containing defined regulatory elements provide novel insights into pathogen- and wound-induced signalling. Plant Cell 14: 749–762 (2002).
- Ogawa R. Construction of strong mammalian promoters by random cis-acting element elongation. Biotechniques 42: 628-632 (2007).
- Edelman G. M., Meech R., Owens G. C. & Jones F. S. Synthetic promoter elements obtained by nucleotide sequence variation and selection for activity. PNAS 97: 3038-43 (2000).
- Ellis T., Wang X. & Collins J. J. Diversity-based, model-guided construction of synthetic gene networks with predicted functions. Nature Biotechnology 27: 465-471 (2009).
- Tornoe J. Generation of a synthetic mammalian promoter library by modification of sequences spacing transcription factor binding sites. Gene 297: 21-32 (2002).
- Heintzman N. D. & Ren B. The gateway to transcription: identifying, characterizing and understanding promoters in the eukaryotic genome. Cellular and Molecular Life Science 64: 386-400 (2007).
- Stemmer W. P., Crameri A., Ha K. D., Brennan T. M. & Heyneker H. L. Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides. Gene 164: 49-53 (1995).
- Rattner A. NF-κB activates the HIV promoter in neurons. EMBO 12: 4261–4267 (1993).
- Yokoyama D. K., Ohler U. & Wray G. A. Measuring spatial preferences at fine-scale resolution identifies known and novel cis-regulatory element candidates and functional motif-pair relationships. Nuc Acids Res: 1-21 (2009).
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Stable cell line
- Zhou H. Development of site-specific integration system to high-level expression recombinant proteins in CHO cells. Chinese journal of biotechnology 23: 756-62 (2007).
- Andrews B. J., Proteau G. A., Beatty L. G. & Sadowski P. D. The FLP Recombinase of the 2μ Circle DNA of Yeast: Interaction with Its Target Sequences. Cell 40: 795-803 (1985).
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- Holmberg A., Blomstergren A., Nord O., Lukacs M., Lundeberg J. & Uhlén M. The biotin-streptavidin interaction can be eversibly broken using water at elevated temperatures. Electrophoresis 26(3): 501-10 (2005).
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Outlook and Summary
- Venter M. Synthetic promoters: genetic control through cis engineering. Trends in Plant Science 12: 118-24 (2007).
- Carey M., Smale S. T. & Hughes H., Transcriptional Regulation in Eukaryotes: Concepts, Strategies and Techniques. New York: CSHL: p. 18-25 (2000).
HEARTBEAT Database & Fuzzy Modeling
- Harbison C. T., Gordon D. B., Lee T. I., Rinaldi N. J., Macisaac K. D., Danford T. W., Hannett N. M., Tagne J. B., Reynolds D. B., Yoo J., Jennings E. G., Zeitlinger J., Pokholok D. K., Kellis M., Rolfe P. A., Takusagawa K. T., Lander E. S., Gifford D. K., Fraenkel E. & Young R. A. Transcriptional regulatory code of a eukaryotic genome. Nature 431: 99-104 (2004).
- Hu Z., Killion P. J. & Iyer V. R. Genetic reconstruction of a functional transcriptional regulatory network. Nature Genet. 39: 683-687 (2007).
- Gertz J., Siggia E. D. & Cohen B. A. Analysis of combinatorial cis-regulation in synthetic and genomic promoters. Nature 457: 215-218 (2009).
- Roider H. G., Kanhere A., Manke T. & Vingron M. Predicting transcription factor affinities to DNA from a biophysical model. Bioinformatics 23: 134-141 (2006).
- Andrianantoandro E., Basu S., Karig D. K. & Weiss R. Synthetic biology: new engineering rules for an emerging discipline. Mol Sys Biol 2: article number 0028 (2006).
- Alberts B., Johnson A., Walter P. & Lewis J. Molecular Biology of the Cell. 5th edition, 2008. Garland Science, Chapter 6
- Vardhanabhuti S., Wang J. & Hannenhalli S. Position and distance specificity are important determinants of cis-regulatory motifs in addition to evolutionary conservation. Nucl Acid Res 35: 3203-3213 (2007).
- Yokoyama K. D., Ohler U. & Wray G. A. Measuring spatial preferences at fine-scale resolution identifies known and novel cis-regulatory element candidates and functional motif-pair relationships. Nucl Acid Res: 1-21 (2009).
- Nelles O. Nonlinear System Identification. Springer, 2000.
- Bosl W. J. BMC systems biology 1, 13 (2007).
- Mathematical modeling of the lambda switch: a fuzzy logic approach.
- B. B. Aldridge, J. Saez-Rodriguez, J. L. Muhlich et al., PLoS computational biology 5 (4), e1000340 (2009).
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