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This is the first template of the TU Delft 2009 iGEM team wiki! On this page information about the project and its progress can be found.

The Team

This is the second year the TU Delft participates in the iGEM competition. The group consists of : (list of members to come here)

a number of instructors and a lot of advisors, willing to help out and think with us when this is necessary. An overview of the people involved and our competences can be found on the team page.

The Meetings

Minutes, action points

April 7th, 2009

Orr

• Bologna 2008 - Ecoli.PROM: an Erasable and Programmable Genetic Memory with E. coli

The Bologna team created here a genetic memory for E.coli that would switch between two states as a response to a certain signal (a UVc signal would inhibit Lex A (an inhibitor of LacI), thus allowing the production of LacI, whereas an IPTG signal would inhibit LacI and allow the production of TetR).

• Cambridge 2008 - iBrain: Foundations for an Artificial Nervous System using Self-Organizing Electrical Patterning

In this project, the Cambridge team decided to do three simultaneous sub-projects: one involved the creation of an artificial neurological system for E.coli (using potassium channels to transfer the ion and thus allow for a gradient of the ions), the second involved generating Turing patterns in order to integrate two signalling systems into Bacillus subtilis, and the third part involved generating standardized tools and techniques for B. subtilis. We learned from this project an important lesson: quality is definitely more important than quantity, and there is no point of doing many simultaneous experiments if we cannot finish any one of them properly.

• KULeuven 2008 - Dr. Coli, the bacterial drug delivery system

In this project, the KU Leuven team presented the idea of using E.coli as a transporter of medication in such a way that it would be targeted at a specific location. Furthermore, the E.coli would react to the presence of foreign organisms and would express certain proteins to destroy them, followed by it's self destruction after the area would be completely cured. It is important to emphasise that the project was not intended to produce a specific medication to a specific disease, but merely as a way to show that the general concept of curing a disease in a direct manner is possible.

Sriram

• Illinois - Biomolecular fluorescence biosensor system: cell bases biosensor system

• Ljubljana, Slovenia - Virotrap - A synthetic biology approach against HIV

• Ljubljana, Slovenia - Engineered Human cells - say no to sepsis

Tim Weenink

• ESBS Strasbourg - Binary generation counting in Yeast

• University of Ottowa - Puslegenerator in Yeast

• Calgary Wetware - Quorum coupled bacteriocin release (engineering a champion)

17th April 2009

Tim Vos

• MIT - Biogurt: A Sustainable and Savory Drug Delivery System

• Groningen - Conway’s Game of Life in real life

• UFreiburg - Modular Synthetic Receptor System

Daniel

• Harvard - bactricity

• ETH Zurich - Random walks towards the minimal genome

• Slovenia - Immunobricks

Saeed

• Caltech - Engenering multi-functional probiotic bacteria

• Heidelberg - Ecolicense to kill

• Valencia - Hot Yeast

You can write a background of your team here. Give us a background of your team, the members, etc. Or tell us more about something of your choosing. Welcome to the Wiki of the TU Delft team for iGEM 2009. The site is still under construction, but as soon as it is finished, we hope to keep with the standards of the TU Delft team last year.
With our 7 participants and 4 instructors, we are enthusiastic to start working on our project (whatever it may be).	Your team picture
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