References
Introduction
- "Synthetic Biology. Applying Engineering to Biology". Report of a NEST High-Level Expert Group. European Commission, Directorate-General for Research. Available online at http://www.synbiosafe.eu/uploads///pdf/EU-highlevel-syntheticbiology.pdf
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- Goodman, C. Engineering ingenuity at iGEM. Nat Chem Biology 4:13. (2008)
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- Ducrest A-L., Amacker M., Lingner J., Nabholz M. Detection of promoter activity by flow cytometric analysis of GFP reporter expression. Nucleic Acids Res. 30, e65 (2002).
- Venter, M. Synthetic promoters: genetic control through cis engineering. Trends in Plant Science 12, 118-124 (2007). (and the references cited therein)
- Ogawa, R. Construction of strong mammalian promoters by random cis-acting element elongation. Biotechniques 42, 628-632 (2007).
- Tornoe, J. Generation of a synthetic mammalian promoter library by modification of sequences spacing transcription factor binding sites. Gene 297, 21-32 (2002).
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Natural Promoters
- Alberts, B., Johnson A., Walter P., Lewis J. Molecular Biology of the Cell, 4th edition, 2008. Garland Science, Chapter 6, p. 357-359.
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Synthetic Promoters
- Alberts, B., Johnson A., Walter P., Lewis J. Molecular Biology of the Cell, 5th edition, 2008. Garland Science, p. 432-453
- Fussenegger M., Weber, W. Engineering of Synthetic Mammalian Gene Networks. Chemistry and Biology 16, 287-297 (2009).
- Gossen M., Bujard, L. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. PNAS 89, 5547-5551 (1992).
- Dorer D. E., Nettelbeck, D. Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis. Advanced Drug Delivery Reviews 61, 554-557 (2009).
- Venter M. Synthetic promoters: genetic control through cis engineering. Trends in Plant Science 12, 118-124 (2007). (and the references cited therein)
- Rushton P. J., Reinstädler A., Lipka V., Lippok B., Somssich I. E. Synthetic plant promoters containing defined regulatory elements provide novel insights into pathogen- and wound-induced signalling. Plant Cell 14, 749–762 (2002).
- Ogawa R. Construction of strong mammalian promoters by random cis-acting element elongation. Biotechniques 42, 628-632 (2007).
- Edelman G. M., Meech R., Owens G. C., Jones F. S. Synthetic promoter elements obtained by nucleotide sequence variation and selection for activity. PNAS 97, 3038-43 (2000).
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- Tornoe J. Generation of a synthetic mammalian promoter library by modification of sequences spacing transcription factor binding sites. Gene 297, 21-32 (2002).
- Heintzman N. D., Ren B. The gateway to transcription: identifying, characterizing and understanding promoters in the eukaryotic genome. Cellular and Molecular Life Science 64, 386-400 (2007).
- Stemmer W. P., Crameri A., Ha K. D., Brennan T. M., Heyneker H. L. Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides. Gene 164, 49-53 (1995).
- Rattner A. NF-κ B activates the HIV promoter in neurons. EMBO 12, 4261–4267 (1993).
- Yokoyama D. K., Ohler U., Wray G. A. Measuring spatial preferences at fine-scale resolution identifies known and novel cis-regulatory element candidates and functional motif-pair relationships. Nuc Acids Res, 1-21 (2009).
- del Val C., Pelz O., Glatting K-H, Barta E., Hotz-Wagenblatt A. PromoterSweep: a tool for identification of transcription factor binding site. Theor Chem Acc (in press)
- Ghosh S., May M. J., Kopp E. B. Rel/NF-κB and IKB proteins: an overview. Seminars in Cancer Biology, 8, 63-73 (1997).
- Moyano P.& Rotwein P. Mini-review: estrogen action in the uterus and insulin-like growth factor-I. Growth Hormone & IGF Research, 14, 431-435 (2009).
Stable cell line
- Zhou, H. Development of site-specific integration system to high-level expression recombinant proteins in CHO cells. Chinese journal of biotechnology 23: 756-62 (2007)
- Andrews, B. J., Proteau, G. A., Beatty, L. G. & Sadowski, P. D. The FLP Recombinase of the 2μ Circle DNA of Yeast: Interaction with Its Target Sequences. Cell 40: 795-803 (1985)
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- Holmberg A., Blomstergren A., Nord O., Lukacs M., Lundeberg J., Uhlén M. The biotin-streptavidin interaction can be eversibly broken using water at elevated temperatures. Electrophoresis 26(3):501-10. (2005)
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Outlook and summary
- Venter M., Synthetic promoters: genetic control through cis engineering, Trends in Plant Science, 12:118-12
- Carey M., Smale S. T., Hughes H., Transcriptional Regulation in Eukaryotes: Concepts, Strategies and Techniques. New York:CSHL, p. 18-25 (2000)
Modeling
HEARTBEAT Fuzzy Modeling
- Harbison C. T., Gordon D. B., Lee T. I., Rinaldi N. J., Macisaac K. D., Danford T. W., Hannett N. M., Tagne J. B., Reynolds D. B., Yoo J., Jennings E. G., Zeitlinger J., Pokholok D. K., Kellis M., Rolfe P. A., Takusagawa K. T., Lander E. S., Gifford D. K., Fraenkel E., Young R. A. Transcriptional regulatory code of a eukaryotic genome. Nature 431, 99-104 (2004).
- Hu, Z., Killion, P. J. & Iyer, V. R. Genetic reconstruction of a functional transcriptional regulatory network. Nature Genet. 39, 683-687 (2007).
- Gertz, J., Siggia E. D. & Cohen, B. A. Analysis of combinatorial cis-regulation in synthetic and genomic promoters. Nature 457. 215-218 (2009)
- Roider H. G., Kanhere A., Manke T., Vingron M. Predicting transcription factor affinities to DNA from a biophysical model. Bioinformatics 23, 134-141 (2006)
- Andrianantoandro E., Basu S., Karig D. K., Weiss R. Synthetic biology: new engineering rules for an emerging discipline. Mol Sys Biol (2006)
- Alberts, B., Johnson A., Walter P., Lewis J. Molecular Biology of the Cell, 5th edition, 2008. Garland Science, Chapter 6
- Vardhanabhuti, S., Wang, J. & Hannenhalli, S. Position and distance specificity are important determinants of cis-regulatory motifs in addition to evolutionary conservation. Nucl Acid Res 35, 3203-3213 (2007).
- Yokoyama, K. D., Ohler, U. & Wray, G. A. Measuring spatial preferences at fine-scale resolution identifies known and novel cis-regulatory element candidates and functional motif-pair relationships. Nucl Acid Res, 1-21 (2009)
- Nelles, O. Nonlinear System Identification. Springer, 2000.
- Bosl, W. J. BMC systems biology 1, 13 (2007).
- Mathematical modeling of the lambda switch:a fuzzy logic approach.
- B. B. Aldridge, J. Saez-Rodriguez, J. L. Muhlich et al., PLoS computational biology 5 (4), e1000340 (2009).
Measurement
- Kelly J. R., Rubin A. J., Davis J. H., Ajo-Franklin C. M., Cumbers J., Czar M. J., de Mora K., Glieberman A. L., Monie D. D., Endy D. Measuring the activity of BioBrick promoters using an in vivo reference standard. Journal of Biological Engineering 3 (2009).
- Endy, D., Deese I. Adventures in synthetic biology (comic) Nature 438, 449-453 (2005). Available online at [http://www.nature.com/nature/comics/syntheticbiologycomic/index.html nature.com]
- Alberts, B., Johnson A., Walter P., Lewis J. Molecular Biology of the Cell, 5th edition, 2008. Garland Science, Chapter 6
- http://www.promega.com/tbs/tm058/tm058.html
- Zhou, H. Development of site-specific integration system to high-level expression recombinant proteins in CHO cells. Chinese journal of biotechnology 23: 756-62 (2007)
- Alberts, B., Johnson A., Walter P., Lewis J. Molecular Biology of the Cell, 5th edition, 2008. Garland Science, Chapter 7, p. 467-476
- Zhu, X. D. Sadowski P. D. Cleavage-dependent Ligation by the FLP Recombinase. J Biol Chem 270, 23044-23054 (1995).
- York J. D., Odom A. R., Murphy R., Ives E. B., Wente S. R. A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. Science 285, 96-100 (1999).
- Alberts, B., Johnson A., Walter P., Lewis J. Molecular Biology of the Cell, 5th edition, 2008. Garland Science) Chapter 7, p. 905-908
- Tornoe, J. Generation of a synthetic mammalian promoter library by modification of sequences spacing transcription factor binding sites. Gene 297, 21-32 (2002),
- Alberts, B., Johnson A., Walter P., Lewis J. Molecular Biology of the Cell, 5th edition, 2008. Garland Science, Chapter 7, p. 492
- Ducrest, A-L et al. Detection of promoter activity by flow cytometric analysis of GFP reporter expression. Nucleic Acids Res. 30, e65 (2002).
- Rushton P. J., Reinstädler A., Lipka V., Lippok B., Somssich I. E. Synthetic plant promoters containing defined regulatory elements provide novel insights into pathogen- and wound-induced signalling. Plant Cell 14, 749-762 (2002)
- Degenhardt T., Rybakova K. N., Tomaszewska A., Moné M. J., Westerhoff H. V., Bruggeman F. J., Carlberg C. Population-Level Transcription Cycles Derive from Stochastic Timing of Single-Cell Transcription. Cell 138, 489-501 (2009).
- Lottspeich, F. and Engels, J. W.: "Bioanalytik" (Book. 2nd edition, 2006. Spektrum Akademischer Verlag) Chapter 5, p. 95-96.
- http://www1.qiagen.com/Products/RnaStabilizationPurification/RNeasySystem/RNeasyPlantMini.aspx
- http://www1.qiagen.com/products/automation/qiacube.aspx
- http://www1.qiagen.com/literature/render.aspx?id=398
Material and Methods
Eukaryopedia
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