Team:Aberdeen Scotland/parameters

Internal Dynamics Parameters

When modeling any process, it is essential to use parameters which reflect reality, otherwise the model will not give accurate predictions. Thus we spend a considerable time researching, analysing and estimating parameters so that our model will reflect real life behaviour as accuratly as possible.

Parameter	Description	Value	Reference
mRNA	Degradation of mRNA	0.003	1
X	Degradation of X	0.00000802	2
Y	Degradation of Y	0.00000802	4
λ-CI	Degradation of lambda CI	0.002888	6
LacI	Degradation of LacI	0.001155	8
TetR	Degradation of TetR	0.00288811	10
Holin	Degradation of Holin	0.0002	guessed; half-life of an hour
Endolysin	Degradation of Endolysin	0.0002	guessed; half-life of an hour
Antiholin	Degradation of Antiholin	0.0002	guessed; half-life of an hour
LuxI	Degradation of LuxI	0.002888	tagged; half-life of 4 min
LuxR	Degradation of LuxR	0.0002	0
HSL	Degradation of HSL	0.00016667	0; value for AHL
Protein	Translation rate of Protein	0.1	2
	Rate of production of HSL from LuxI	0.45	2
HSL	Rate of diffusion of HSL in/out of the cell	0.4	2
IPTG	Rate of diffusion of IPTG in/out of the cell	0.014	2
P	Rate of formation of the HSL-LuxI complex	0.00010	2
-P	Rate of dissociation of the HSL-LuxI complex	0.003	2
-P	Rate of dissociation of the HSL-LuxI complex	0.003	2

References