Team:Aberdeen Scotland/modeling

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University of Aberdeen iGEM 2009

Introduction

Aberdeen Modeling Team.JPG

From left to right: Rory, James, Nick, Stuart, Liam and Annika

Our modeling team consists of six undergraduates, four of whom study maths and physics, one studying physics and one chemical engineering. Due to the complex nature of the project, we need good predictions from mathematical simulations to help predict and understand our system. We are mainly programing our simulations in C and Matlab but we have also used Matlab's Sim-Biology toolbox for some sensitivity analysis.

We have split our modeling into 3 main sections.


The internal dynamics of our system, which includes mRNA transcription and protein translation.

 


Modeling the chemotaxis of e. coli and how they move towards a food source.

 


In our system, quorum sensing is a behaviour which we wish to exploit, to do this it is essential to model the system to guarantee it responds to inputs correctly.