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Team:Imperial College London/M2/Rfal
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Revision as of 10:49, 12 October 2009 by JamesField (Talk | contribs)
Rfal
In the majority of E.coli, the enzyme Rfal joins the O-antigen to the membrane-bound lipid core molecule. Since the K-12 strain has an insertion mutation in the gene coding for O-antigen, the enzyme Rfal is free to join colanic acid to the lipid core.
The tethering of colanic acid to the cell will faciliate the encapsulation of individual cells confering greater acid resistance.
