Team:Aberdeen Scotland/hillinput

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University of Aberdeen iGEM 2009

Repression of a Promoter

During repression of a promoter a repressor protein, X, binds to a DNA site of the promoter, D. The product of this binding process is [XD]. [XD] can also fall apart into [X] and [D] again:

 

(I)



where kon describes the collisions of X and D that occur per time per protein at a given concentration and koff determines the strength of the chemical binding X and D. In form of a differential equation, the rate of change of [XD] is described by


 

(II)