Team:Imperial College London/M1

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(Phenylalanine Hydroxylase)
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Phenylalanine Hydroxylase (PAH) is an enzyme that breaks down the amino acid phenylalanine into tyrosine. By introducing this enzyme into the digestive system with <i>The E.ncapsulator</i>'s unique drug delivery mechanism, we hope to treat the sufferers of PKU.
Phenylalanine Hydroxylase (PAH) is an enzyme that breaks down the amino acid phenylalanine into tyrosine. By introducing this enzyme into the digestive system with <i>The E.ncapsulator</i>'s unique drug delivery mechanism, we hope to treat the sufferers of PKU.
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To find out more about phenylketonuria and PAH, click [[Team:Imperial_College_London/M1/PKU |here]].
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=Overview=
=Overview=

Revision as of 13:40, 14 September 2009

Module 1 is the first module of our system. This module is responsible for the production of the protein of interest. Although The E.ncapsulator is designed to be versatile with regard to which protein is to be produced, we have chosen two enzymes as demonstration, phenylalanine hydroxylase and cellulase.

Cellulase

Cellulase is an enzyme that breaks down cellulose to glucose. More information on cellulase can be found here

Phenylalanine Hydroxylase


Phenylketonuria is a digestive disorder caused by an inability of the body to break down the amino acid phenylalanine. The amino acid accumulates in the blood, and can cause serious health problems for afflicted individuals. Current treatments for the condition revolve around following a strict very low protein diet.

Phenylalanine Hydroxylase (PAH) is an enzyme that breaks down the amino acid phenylalanine into tyrosine. By introducing this enzyme into the digestive system with The E.ncapsulator's unique drug delivery mechanism, we hope to treat the sufferers of PKU.

To find out more about phenylketonuria and PAH, click here.


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Module 1: Genetic circuit


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