Team:Newcastle/Cadmium sensing
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==Cadmium Sensing== | ==Cadmium Sensing== | ||
The metal sensing proteins we intend to use are ''yozA'' (''czrA'') and ''arsR'' which both bind cadmium as well as zinc cobalt and nickle, and arsenic, silver and copper respectively [2].These proteins are repressor proteins which also bind DNA preventing transcription of downstream CDS. The repressor proteins however release the DNA to preferentially bind cadmium [2] allowing transcription to occur. These proteins therefore allow selective sensing of cadmium in the form of an AND gate, a model for which can be seen in our modelling section. | The metal sensing proteins we intend to use are ''yozA'' (''czrA'') and ''arsR'' which both bind cadmium as well as zinc cobalt and nickle, and arsenic, silver and copper respectively [2].These proteins are repressor proteins which also bind DNA preventing transcription of downstream CDS. The repressor proteins however release the DNA to preferentially bind cadmium [2] allowing transcription to occur. These proteins therefore allow selective sensing of cadmium in the form of an AND gate, a model for which can be seen in our modelling section. | ||
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Revision as of 09:38, 22 July 2009
Cadmium Sensing
The metal sensing proteins we intend to use are yozA (czrA) and arsR which both bind cadmium as well as zinc cobalt and nickle, and arsenic, silver and copper respectively [2].These proteins are repressor proteins which also bind DNA preventing transcription of downstream CDS. The repressor proteins however release the DNA to preferentially bind cadmium [2] allowing transcription to occur. These proteins therefore allow selective sensing of cadmium in the form of an AND gate, a model for which can be seen in our modelling section.
News
Events
- 20 – 21 June 2009 - Europe workshop (London)
- 23 – 24 June 2009 - UK iGEM meetup (Edinburgh)
- 23 October Practice Presentation (Newcastle)
- 23 October T-shirts are ready
- 27 October Practice Presentation (Sunderland)
- 27 October Poster is ready
- 30 October – 2 November 2009 - Jamboree (Boston)
Social Net
- Newcastle iGEM Twitter
- [http://www.facebook.com/home.php#/group.php?gid=131709337641 Newcastle on Facebook]
- [http://www.youtube.com/user/newcastle2009igem Newcastle Youtube Channel]