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Team:EPF-Lausanne/Modeling
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==To do== | ==To do== | ||
;- Model allosteric interactions between LOVTAP & TrpR: | ;- Model allosteric interactions between LOVTAP & TrpR: | ||
Revision as of 14:22, 27 July 2009
Contents |
To do
- - Model allosteric interactions between LOVTAP & TrpR
- What will be done:
- - Model of LOVTAP in dark phase
- - Model of LOVTAP in light phase
- - Characterize how the J-alpha helix changes
- - Model sturctural changes that enhance the switch feature of LOVTAP e.g. in dark phase: really weak interaction between LOVTAP and the corresponding DNA sequence, in light phase: strong binding of LOVTAP on DNA.
To envisage
- Molecular mutationnal assay
