Team:EPF-Lausanne/Team

From 2009.igem.org

(Difference between revisions)
Line 11: Line 11:
<br>
<br>
<br>
<br>
-
 
-
 
-
<html>
 
-
<!-- CSS -->
 
-
 
-
<link rel="stylesheet" type="text/css" href="https://2008.igem.org/wiki/index.php?title=User:Avdmeers/wiki/teammap.css&action=raw&ctype=text/css" />
 
-
 
-
<style type="text/css">
 
-
    #bioscenter-box {background: #5cc7dd;}
 
-
    #kuleuven-box {background: #77ffff;}
 
-
    #team-box {background: #ffff88;}
 
-
    #project-box {background: #aadd66;}
 
-
    #modeling-box {background: #77ffff;}
 
-
 
-
    #kul div {text-align: justify;}
 
-
</style>
 
-
 
-
<!-- CSS: IE FIXES -->
 
-
<!--[if IE]>
 
-
<style type="text/css">
 
-
    #home-content>div {border-color:#747474;}
 
-
    #home-sidebar table.month {margin:0 auto;background-color:transparent;}
 
-
</style>
 
-
<![endif]-->
 
-
 
-
<!-- JAVASCRIPT -->
 
-
<script type="text/javascript" src="http://www.kuleuven.be/bioscenter/igem/js/ui.core.js"></script>
 
-
<script type="text/javascript" src="http://www.kuleuven.be/bioscenter/igem/js/ui.tabs.js"></script>
 
-
<script type="text/javascript" src="http://www.kuleuven.be/bioscenter/igem/js/jquery.corner.js"></script>
 
-
<script type="text/javascript">
 
-
$(function() {
 
-
    $('#bioscenter-box > ul').tabs({ fx: { opacity: 'toggle', height: 'toggle'} });
 
-
    $('#kuleuven-box > ul').tabs({ fx: { opacity: 'toggle', height: 'toggle'} });
 
-
    $('#team-box > ul').tabs({ fx: { opacity: 'toggle', height: 'toggle'} });
 
-
    $('#project-box > ul').tabs({ fx: { opacity: 'toggle', height: 'toggle'} });
 
-
    $('#modeling-box > ul').tabs({ fx: { opacity: 'toggle', height: 'toggle'} });
 
-
 
-
    $('#bioscenter-box').corner("bottom");
 
-
    $('#kuleuven-box').corner("bottom");
 
-
    $('#team-box').corner("bottom");
 
-
    $('#project-box').corner("bottom");
 
-
    $('#modeling-box').corner("bottom");
 
-
});
 
-
</script>
 
-
 
-
<script type="text/javascript">
 
-
function CngTxt(id,txt){
 
-
var obj=document.getElementById(id);
 
-
if (txt){ obj.innerHTML=txt; }
 
-
else { obj.innerHTML='<br>scroll over the pictograms to get a short description or click on them to go to the corresponding page'; }
 
-
}
 
-
</script>
 
-
 
-
<!-- Script for preloading images into webpage -->
 
-
<script type="text/javascript">
 
-
Image1 = new Image(665,499)
 
-
Image1.src = "https://static.igem.org/mediawiki/2008/1/17/StudentsKULBlackWhite.JPG"
 
-
 
-
Image2 = new Image(215,54);
 
-
Image2.src = "https://static.igem.org/mediawiki/2008/5/5d/KUL_iGEM_link2.png"
 
-
</script>
 
-
 
-
<script type="text/javascript">
 
-
function popup(mylink, windowname)
 
-
{
 
-
if (! window.focus)return true;
 
-
var href;
 
-
if (typeof(mylink) == 'string')
 
-
  href=mylink;
 
-
else
 
-
  href=mylink.href;
 
-
window.open(href, windowname, 'width=640,height=480,scrollbars=yes');
 
-
return false;
 
-
}
 
-
</script>
 
-
 
-
</html>
 
-
<div id="home">
 
-
 
-
<html>
 
-
<div class="alert-box">
 
-
Our wiki has been frozen. For future updates we advise you to redirect to iGEM's <a href="https://2008.igem.org/Main_Page">Main Page</a>. To follow our adventure at the Jamboree in Boston, keep an eye on our online <a href="http://igemkuleuven.wordpress.com/">BLOG</a>.
 
-
</div>
 
-
</html>
 
-
 
-
<br />
 
-
 
-
<html>
 
-
<!-- HEADER -->
 
-
<div id="home-header"  style="overflow:hidden">
 
-
 
-
<!-- COUNTDOWN -->
 
-
<div class="countdown">
 
-
<div style="float:left;clear:both">
 
-
<embed src="http://www.oneplusyou.com/bb/files/countdown/countdown.swf?co=075A90&date_month=11&date_day=09&date_year=1&un=IGEM JAMBOREE 2008&size=normal&mo=11&da=09&yr=2008" type="application/x-shockwave-flash" pluginspage="http://www.macromedia.com/go/getflashplayer" width="240" height="80" wmode="transparent"></embed>
 
-
</div>
 
-
<div style="float:left;clear:both;background:white;width:240px;height:20px"></div>
 
-
</div>
 
-
 
-
<h2>Welcome to the KULeuven IGEM 2008 Homepage!</h2>
 
-
<p>Enjoy the hard work we delivered, feel free to contact us at <a href="mailto:igem@kuleuven.be?SUBJECT=IGEM 2008">igem@kuleuven.be</a> and visit our university/sponsor (<a href="http://www.kuleuven.be/bioscenter">BioSCENTer</a>) <a href="http://www.kuleuven.be/bioscenter/igem"><b>iGEM page</b></a>!</p>
 
-
 
-
</div>
 
-
 
-
<!-- MAIN -->
 
-
<div id="home-main">
 
-
 
-
<!-- CONTENT -->
 
-
<div id="home-content">
 
-
 
-
<!-- CONTENT: BIOSCENTER -->
 
-
<div id="bioscenter-box">
 
-
    <h3>Synthetic Biology: BioSCENTer and iGEM</h3>
 
-
    <ul>
 
-
    <li><a href="#bioscenter-1"><span>On Synthetic Biology</span></a></li>
 
-
    <li><a href="#bioscenter-2"><span>On IGEM</span></a></li>
 
-
    </ul>
 
-
 
-
<!-- CONTENT: BIOSCENTER: SYNTHETIC BIOLOGY -->
 
-
<div id="bioscenter-1">
 
-
<p>
 
-
<a href="http://syntheticbiology.org">Synthetic biology</a> is a new challenge in biosciences. It combines biology and engineering principles to design and build new biological functions and systems. Examples are abound: cancer cell invading bacteria, microbes that take pictures, antimalarial drug producers,... The advantage of using living systems for these purposes is that, once they are designed and built, they are self-reproducible. The challenge, however, lies exactly within the design and construction: making biological circuits and devices as robust and predictive as their electrical counterparts. <a href="http://www.kuleuven.be/bioscenter/igem/?go=syntheticbiology">...</a>
 
-
</p>
 
-
<ul class="more">
 
-
<li><a href="http://www.kuleuven.be/bioscenter/igem/?go=syntheticbiology">Read the whole page</a></li>
 
-
</ul>
 
-
</div>
 
-
 
-
<!-- CONTENT: BIOSCENTER: IGEM -->
 
-
<div id="bioscenter-2">
 
-
<img class="floatright" src="https://static.igem.org/mediawiki/2008/1/1e/IGEM_logo_1.png" />
 
-
<p>
 
-
The <a href="https://2008.igem.org">international Genetically Engineered Machine competition (iGEM) or iGEM competition</a> is a synthetic biology competition for multidisciplinary teams of undergraduate students. It was first organized in 2004 by Drew Endy, Randy Rettberg and Tom Knight of MIT with two goals in mind: to yield new ideas in synthetic biology and to form the future researchers in this new scientific community. Whereas 5 US teams competed in 2004, the 2007 edition already had 750 students and advisors grouped in 54 teams from 19 countries. This year, the competition already counts 83 teams!
 
-
<br><br>
 
-
The core of the iGEM competition is to design and build a “new genetic machine” with <a href="http://partsregistry.org">BioBricks</a>. BioBricks are standardized, off the shelf biological parts that are used by genetic network designers. All BioBricks that were made during previous iGEM competitions are registered and documented in the Registry of Standard Biological Parts. Each iGEM competition thus starts from the efforts of the previous years.
 
-
</p>
 
-
<ul class="more">
 
-
<li><a href="http://www.kuleuven.be/bioscenter/igem/?go=competition">Read the whole page</a></li>
 
-
<li><a href="http://www.kuleuven.be/bioscenter/igem/?go=people2008">More on our team</a></li>
 
-
</ul>
 
-
</div>
 
-
 
-
</div>
 
-
 
-
<!-- CONTENT: KULEUVEN -->
 
-
<div id="kuleuven-box">
 
-
    <h3>Leuven</h3>
 
-
    <ul>
 
-
    <li><a href="#kuleuven-1"><span>KULeuven</span></a></li>
 
-
    </ul>
 
-
<!-- CONTENT: KULEUVEN DESCRIPTION -->
 
-
<div id="kuleuven-1">
 
-
<img class="floatright" width="300" heigth="300" src="https://static.igem.org/mediawiki/2008/5/59/Leuven_by_night.jpg" />
 
-
<p>
 
-
The University of Leuven was founded almost six hundred years ago. Throughout the centuries people have always occupied center stage at the <a href="http://www.kuleuven.be/english">Katholieke Universiteit Leuven</a>.
 
-
The University's academic fame has attracted scholars and scientists as Justus Lipsius, Gerard Mercator and Andreas Vesalius who have all made valuable contribution to the European intellectual life.
 
-
The University of Leuven can look back on a glorious past, but it also moves with the times.
 
-
The University's educational concept is modern, with research activities focused on the needs and aspirations of contemporary people and society.
 
-
The University of Leuven is famous not just within the borders of Belgium, but far beyond as well. Being a very lively city of and for students, Leuven aspires to maintain that reputation. In contrast to most university cities, Leuven does not have a closed campus. The University buildings are spread throughout the city and were originally built for completely different purposes.
 
-
</p>
 
-
</div>
 
-
 
-
</div>
 
-
 
-
<!-- CONTENT: TEAM -->
 
-
<div id="team-box">
 
-
    <h3>The Team</h3>
 
-
    <ul>
 
-
    <li><a href="#team-1"><span>Meet the team</span></a></li>
 
-
    </ul>
 
-
 
-
<!-- CONTENT: TEAM: IMAGE MAP -->
 
-
<div id="team-1">
 
-
<p>
 
-
The KULeuven team consists of 12 enthusiastic students selected out of three faculties, 4 civil engineers, 4 bio-engineers and 4 biochemists. More information on the team members can be found on the <a href="https://2008.igem.org/Team:KULeuven/Team/Students">Students page</a> or by scrolling over the heads of the students.
 
-
</p>
 
-
<script>
 
-
function haxbackground(){
 
-
    document.getElementById('cartoonmap').style.backgroundImage='url(https://static.igem.org/mediawiki/2008/1/17/StudentsKULBlackWhite.JPG)';
 
-
}
 
-
function unhaxbackground(){
 
-
    document.getElementById('cartoonmap').style.backgroundImage="url('https://static.igem.org/mediawiki/2008/5/57/StudentsKUL.JPG')";
 
-
}
 
-
</script>
 
-
<dl id="cartoonmap">
 
-
 
-
    <dt>Maarten Breckpot</dt>
 
-
    <dd id="maarten"><a href="https://2008.igem.org/User:Maarten" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Maarten Breckpot</div>
 
-
        <div class="rest"> <br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 1st Master of Applied Sciences and Engineering – Mathematical Engineering </font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font> </div></span>
 
-
    </a></dd>
 
-
 
-
    <dt>Nick Van Damme</dt>
 
-
    <dd id="nick"><a href="https://2008.igem.org/User:Nickvd" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Nick Van Damme</div>
 
-
        <div class="rest"><br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 1st Master of Applied Sciences and Engineering – Mathematical Engineering </font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font> </div></span>
 
-
    </a></dd>
 
-
 
-
        <dt>Benjamien Moeyaert</dt>
 
-
    <dd id="benjamien"><a href="https://2008.igem.org/User:Bmoeyaert" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Benjamien Moeyaert</div>
 
-
        <div class="rest"><br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 3rd Bachelor of Biochemistry and Biotechnology</font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font> </div></span>
 
-
    </a></dd>
 
-
 
-
        <dt>Stefanie Roberfroid</dt>
 
-
    <dd id="stefanie"><a href="https://2008.igem.org/User:Stefanie" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Stefanie Roberfroid</div>
 
-
        <div class="rest"><br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 3rd Bachelor of Bioscience Engineering – Biomolecular Engineering</font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font> </div></span>
 
-
    </a></dd>
 
-
 
-
        <dt>Dries Vercruysse</dt>
 
-
    <dd id="dries"><a href="https://2008.igem.org/User:Dries" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Dries Vercruysse</div>
 
-
        <div class="rest"><br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 1st Master of Applied Sciences and Engineering - Nanoscience and Nanotechnology</font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font> </div></span>
 
-
    </a></dd>
 
-
 
-
        <dt>Andim Doldurucu</dt>
 
-
    <dd id="andim"><a href="https://2008.igem.org/User:Andim" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Andim Doldurucu</div>
 
-
        <div class="rest"><br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 1st Master of Bioscience Engineering – Nanoscience and Nanotechnology</font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Turkey </font> </div></span>
 
-
    </a></dd>
 
-
 
-
        <dt>Hanne Tytgat</dt>
 
-
    <dd id="hanne"><a href="https://2008.igem.org/User:Hanne" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Hanne Tytgat</div>
 
-
        <div class="rest"><br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 3rd Bachelor of Biochemistry and Biotechnology</font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font> </div></span>
 
-
    </a></dd>
 
-
 
-
        <dt>Elke Van Assche</dt>
 
-
    <dd id="elke"><a href="" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Elke Van Assche</div>
 
-
        <div class="rest"><br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 3rd Bachelor of Bioscience Engineering – Biomolecular Engineering</font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font> </div></span>
 
-
    </a></dd>
 
-
 
-
        <dt>Jan Mertens</dt>
 
-
    <dd id="jan"><a href="https://2008.igem.org/User:Jotaro" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Jan Mertens</div>
 
-
        <div class="rest"><br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 1st Master of Bioscience Engineering – Biomolecular Engineering</font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font> </div></span>
 
-
    </a></dd>
 
-
 
-
        <dt>Nathalie Busschaert</dt>
 
-
    <dd id="nathalie"><a href="https://2008.igem.org/User:BNathalie" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Nathalie Busschaert</div>
 
-
        <div class="rest"><br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 3rd Bachelor of Chemistry </font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font> </div></span>
 
-
    </a></dd>
 
-
 
-
        <dt>Jonas Demeulemeester</dt>
 
-
    <dd id="jonas"><a href="https://2008.igem.org/User:Zeunas" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Jonas Demeulemeester</div>
 
-
        <div class="rest"><br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 1st Master of Biochemistry and Biotechnology</font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font> </div></span>
 
-
    </a></dd>
 
-
 
-
        <dt>Antoine Vandermeersch</dt>
 
-
    <dd id="antoine"><a href="https://2008.igem.org/User:Avdmeers" onmouseover="haxbackground();" onmouseout="unhaxbackground();">
 
-
        <span><div class="first">Antoine Vandermeersch</div>
 
-
        <div class="rest">
 
-
                <br> <b><font size="2.5">Studies:</font></b> <br> <font size="2"> 2nd and 3rd Bachelor of Applied Sciences and Engineering – Electrical and Materials Engineering </font> <br> <b><font size="2.5">Country:</font></b> <br> <font size="2"> Belgium</font>
 
-
                </div></span>
 
-
    </a></dd>
 
-
</dl>
 
-
 
-
 
-
</div>
 
-
 
-
</div>
 
-
 
-
</div><!-- END SIDEBAR -->
 
-
 
-
</div><!-- END HOME -->
 

Revision as of 07:55, 2 September 2009

Contents


Team





Who we are

We are a team of undergraduates with an interdisiplinary background. Most of us are from the life sciences faculty but some are from microengineering, mechanical engineering and chemistry.

Group : from left to right : up : Nicolas G, Christian, Gabriela, Tú, Nathalie, Carine, Nicolas D, Rafael, down : Heidi, Sebastian, Caroline, Mélanie


Back to top


Undergrads




Instructors



Advisors


Back to top


What we want to do

Light-sensitive proteins can easily be found in nature, but they have never been cloned into other cells. In this project, our aim is to design a fusion protein that would allow genetic regulation through light control.

Therefore we are working on cloning strategies that would allow us to fuse a light-sensitive domain (LovTAP in our case) with a regulatory domain (like the Trp operon). The idea is to allow transmission of the conformational change induced by light (on the light-sensitive domain) to the DNA-binding domain. This transmitted conformational change would then result in an increase or decrease of the regulatory domain's affinity for the DNA promoter site.

The overal effect would thus be a genetic expression controlled by light! There would be many applications to such a "switch" : it could kill bacteria at a certain point, stop their growth, or make them express specific proteins...

To improve the change induced by light (which is generally very unstable), we also plan a modeling part where the aim is to find which residue we would have to mutate in order to have a stable protein after the switch.

The advantage of such a system is that we could apply the light on a system and then remove it (not like if we added some liquid on the cells).


Where we are from

We are all studying at EPFL aka the Swiss Institute of Technology of Lausanne. The campus is located near the shore of lake Geneva in the surroundings of the city of Lausanne, 50 km away from Geneva.


Back to top