Team:Slovenia/Coiled-coil polyhedra Results.html
From 2009.igem.org
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Summary
We set to prepare complex polyhedra as well as two-dimensional lattice; both can be constructed from interacting rigid polypeptide rods, assuming the polypeptide being equivalent of DNA origami. This could produce structures that do not exist in nature. Coiled-coil interactions represent the best candidate for this type of assembly as their sequence dictates the selectivity and orientation for interactions with other coiled-coil segments. In the section on modeling we analyzed the potentials of this approach and designed amino acid sequences of their building blocks.
![]() Figure 1: TEM image of the self-assembled nanostructure made of K2 |