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Team:EPF-Lausanne/Modeling
From 2009.igem.org
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:- Model of LOVTAP in light phase | :- Model of LOVTAP in light phase | ||
:- Characterize how the J-alpha helix changes | :- Characterize how the J-alpha helix changes | ||
| - | :- Model | + | :- Model structural changes that enhance the switch feature of LOVTAP e.g. in dark phase: really weak interaction between LOVTAP and the corresponding DNA sequence, in light phase: strong binding of LOVTAP on DNA. |
| - | + | ||
| - | + | ||
==To envisage == | ==To envisage == | ||
Revision as of 13:49, 28 July 2009
Contents |
To do
- - Model allosteric interactions between LOVTAP & TrpR
- What will be done:
- - Model of LOVTAP in dark phase
- - Model of LOVTAP in light phase
- - Characterize how the J-alpha helix changes
- - Model structural changes that enhance the switch feature of LOVTAP e.g. in dark phase: really weak interaction between LOVTAP and the corresponding DNA sequence, in light phase: strong binding of LOVTAP on DNA.
To envisage
- Molecular mutationnal assay
