Team:SJTU-BioX-Shanghai

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Inspired by the natural regulator of circadian bioclock exhibited in most eukaryotic organisms, our team has designed an E.coli-based genetic network with the toxin-antitoxin system so that the bacterium oscillates between two states of dormancy and activity. Potential applications of this project include the preservation of frequently-mutating bacteria, biologic timing, antibiotic resistance, etc.
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Revision as of 09:03, 30 July 2009

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Project introduction. Inspired by the natural regulator of circadian bioclock exhibited in most eukaryotic organisms, our team has designed an E.coli-based genetic network with the toxin-antitoxin system so that the bacterium oscillates between two states of dormancy and activity (more...)

An E.coli-based oscillator of prokaryotic bioclock

Inspired by the natural regulator of circadian bioclock exhibited in most eukaryotic organisms, our team has designed an E.coli-based genetic network with the toxin-antitoxin system so that the bacterium oscillates between two states of dormancy and activity. Potential applications of this project include the preservation of frequently-mutating bacteria, biologic timing, antibiotic resistance, etc.