Team:TUDelft/Synthetic Transcriptional Cascade

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Transcriptional cascades can be seen as temporal programs of successive gene expression (4). This gene configurations (or circuits) have the capability to integrate signals and trigger events after a delay from the initial detection event. As described before, such characteristic is needed in our project; therefore we considered two approaches based on transcriptional cascades. After some preliminary analysis, the approach termed negative synthetic transcriptional cascade was chosen to be developed.
 
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Transcriptional cascades can be seen as temporal programs of successive gene expression (4). This gene configurations (or circuits) have the capability to integrate signals and trigger events after a delay from the initial detection event. As described before, such characteristic is needed in our project; therefore we considered two approaches based on transcriptional cascades. After some preliminary analysis, the approach termed negative synthetic transcriptional cascade was chosen to be developed.

Revision as of 12:31, 15 September 2009

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Synthetic Transcriptional Cascade

Transcriptional cascades can be seen as temporal programs of successive gene expression (4). This gene configurations (or circuits) have the capability to integrate signals and trigger events after a delay from the initial detection event. As described before, such characteristic is needed in our project; therefore we considered two approaches based on transcriptional cascades. After some preliminary analysis, the approach termed negative synthetic transcriptional cascade was chosen to be developed.


Preliminary approaches

Synthetic Transcriptional Cascade: The plan

Results


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