Synthetic Transcriptional Cascade

Transcriptional cascades can be seen as temporal programs of successive gene expression [4]. This gene configurations (or circuits) have the capability to integrate signals and trigger events after a delay from the initial detection event. As described before, such characteristic is needed in our project; therefore we considered two approaches based on transcriptional cascades. After some preliminary analysis, the approach termed negative synthetic transcriptional cascade was chosen to be developed.

• Preliminary approaches

• Synthetic Transcriptional Cascade: The plan

• Results

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