Team:Newcastle/SporulationTuning/Phosphorylation
From 2009.igem.org
Phosphorylation
Phosphorylation stimulates the capacity of Spo0A to bind to its recognition sequence in DNA, known as the 0A-box via its DNA-binding domain, which is located in the C-terminal portion of the protein.[1]
References
[1] Fujita, M., Losick, R. (2005) Evidence that Entry into Sporulation in Bacillus subtilis is Governed by a Gradual Increase in the Level and Activity of the Master Regulator Spo0A. 19: 2236–2244
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