Chapter Ref. Authors Title Year
Current Therapies [1] Lechat P. Pharmacology 2006
Current Therapies [2] Bruguerolle B. Biological rhythms and medications: a source of variability often neglected in pharmacology 2008
Current Therapies [1] Kevin J. Scanlon and al. Cancer Gene Therapy: Challenges and Opportunities 2004
Gene Therapies [2] Gouze JN and al. A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer 2003
Gene Therapies [3] Centre for Genetics Education XXXX

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Chapter Ref. Authors Title Year
Vectorization [1] Couvreur P. L'encapsulation de médicament 2003
Vectorization [2] Andrieux K. and al. Nanotechnology and new drug 2003
Vectorization [3] Torchilin V.P. Recent Approaches to Intracellular Delivery of Drugs and DNA and Organelle Targeting 2006
Vectorization [4] Davis M.E. and al. Nanoparticle therapeutics: an emerging treatment modality for cancer 2008
Vectorization [5] Seow Y. and al. Biological Gene Delivery Vehicles: Beyond Viral Vectors 2009
Vectorization [6] Decroly E. Vectorology 2005
Vectorization [7] Robbins P.D. and al. Viral Vectors for Gene Therapy 1998
Vectorization [8] Wei M.Q. and al. Bacterial targeted tumour therapy-dawn of a new era 2008
Vectorization [9] Ryan R.M. and al. Use of bacteria in anti-cancer therapies 2005
Vectorization [10] Mehnert Solid lipid nanoparticles: Production, characterization and applications 2001
Vectorization [11] Lasic D.D. Liposomes in gene therapy 1996
Vectorization [12] Lutten J. and al. Biodegradable polymers as non-viral carriers for plasmid DNA delivery 2008
Vectorization [13] Jiskoot W. and al. Immunological Risk of Injectable Drug Delivery Systems 2009
Vectorization [14] Head M. and al. Mechanism and computer simulation of immune complex formation, opsonization, and clearance 1996
Vectorization [15] Koide H. and al. Particle size-dependent triggering of accelerated blood clearance phenomenon 2008
Vectorization [16] Ishida T. and al. Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: Effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes 2005
Vectorization [17] Wang XY and al. Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes 2007
Vectorization [18] Tosi M.F. and al. Innate immune responses to infection 2005
Vectorization [19] Linkov I and al. Nanotoxicology and nanomedicine: making hard decisions 2008

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Tissue Vector

Chapter Ref. Authors Title Year
Tissue Vector [1] Ronald S. and al. Antimicrobial mechanisms of phagocytes and bacterial evasion strategies 2009
Tissue Vector [2] Clark B. Inderlied and al. The Mycobacterium avium Complex 1993
Tissue Vector [3] Nisheeth Agarwal and al. Cyclic AMP intoxication of macrophages by a Mycobacterium tuberculosis adenylate cyclase 2009
Tissue Vector [4] Hunter R.L. and al. Pathology of postprimary tuberculosis in humans and mice: contradiction of long-held beliefs 2007
Tissue Vector [5] Axelrod S and al. Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide 2008
Tissue Vector [6] Nicole N van der Wel and al. Subcellular localization of mycobacteria in tissues and detection of lipid antigens in organelles using cryo-techniques for light and electron microscopy 2005
Tissue Vector [7] Claudia Nobrega and al. The thymus as a target for mycobacterial infections 2007

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Cell Vector

Chapter Ref. Authors Title Year
Cell Vector [1] Harrison Echols and al. Genetic Map of Bacteriophage Lambda 1978
Cell Vector [2] Joseph Sambrook and al. Molecular Cloning: A Laboratory Manual (Third Edition) 2001
Cell Vector [3] Court DL and al. A New Look at Bacteriophage lambda Genetic Networks 2007
Cell Vector [4] Ortega ME and al. Bacteriophage Lambda gpNu1 and Escherichia coli IHF Proteins Cooperatively Bind and Bend Viral DNA: Implications for the Assembly of a Genome-Packaging Motor 2006
Cell Vector [5] Feiss M. and al. Bactériophage Lambda Terminase and the Mechanism of Viral DNA Packaging 2005
Cell Vector [6] Hang JQ and al. The Functional Asymmetry of cosN, the Nicking Site for Bacteriophage λ DNA Packaging, Is Dependent on the Terminase Binding Site, cosB 2001
Cell Vector [7] Becker A and al. Bacteriophage lambda DNA : The begginning of the End 1990
Cell Vector [8] Hochschild A and al. The bactériophage lambda cI protein finds an asymmetric solution 2009
Cell Vector [9] Phoebe L.Stewart1 and al. Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization 1997

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Therapeutic Plasmide

Chapter Ref. Authors Title Year
Therapeutic Plasmide [1] Ortega ME et al. Bacteriophage lambda gpNu1 and Escherichia coli IHF proteins cooperatively bind and bend viral DNA: implications for the assembly of a genome-packaging motor 2006
Therapeutic Plasmide [2] Joseph Sambrook and al. Molecular Cloning: A Laboratory Manual (Third Edition) 2001
Therapeutic Plasmide [3] Court DL and al. A New Look at Bacteriophage lambda Genetic Networks 2007
Therapeutic Plasmide [4] Feiss M. and al. Viral Genome Packaging Machines: Genetics, Structure and Mechanism 2005
Therapeutic Plasmide [5] Hang JQ and al. The Functional Asymmetry of cosN, the Nicking Site for Bacteriophage λ DNA Packaging, Is Dependent on the Terminase Binding Site, cosB 2001
Therapeutic Plasmide [6] Becker A and al. Bacteriophage lambda DNA : The begginning of the End 1990
Therapeutic Plasmide [7] Young et al. Effect of a DNA nuclear targeting sequence on gene transfer and expression of plasmids in the intact vasculature 2003

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Antitumor action

Chapitre Ref. Auteurs Titre Année
Antitumor action [1] Chunlin Yang et al Adenovirus-mediated Wild-Type p53 Expression Induces Apoptosis and Suppresses Tumorigenesis of Prostatic Tumor Cells 1995
Antitumor action [2] Corrado Cirielli et al. Adenovirus-mediated wild-type p53 expression induces apoptosis and suppresses tumorigenesis of experimental intracranial human malignant glioma 1999
Antitumor action [3] Su-Ping Ren et al. Adenoviral-mediated transfer of human wild-type p53, GM-CSF and B7-1 genes results in growth suppression and autologous anti-tumor cytotoxicity of multiple myeloma cells in vitro 2006
Antitumor action [4] Zhao-hua Qiu et al Growth suppression and immunogenicity enhancement of Hep-2 or primary laryngeal cancer cells by adenovirus-mediated co-transfer of human wild-type p53, granulocyte-macrophage colony-stimulating factor and B7-1 genes 2002
Antitumor action [5] Zhao-hua Qiu et al. Co-transfer of human wild-type p53 and granulocyte-macrophage colony-stimulating factor genes via recombinant adenovirus induces apoptosis and enhances immunogenicity in laryngeal cancer cells 2001
Antitumor action [6] Markus Reiser et al. Induction of cell proliferation arrest and apoptosis in hepatoma cells through adenoviral-mediated transfer of p53 gene 2000
Antitumor action [7] Louis L. Pisters et al. Evidence That Transfer of Functional p53 Protein Results in Increased Apoptosis in Prostate Cancer 2004
Antitumor action [8] Susan C. Modesitt et al. In Vitro and in Vivo Adenovirus-mediated p53 and p16 Tumor Suppressor Therapy in Ovarian Cancer 2001
Antitumor action [9] Yong-song GUAN et al. Adenovirus-mediated wild-type p53 gene transfer in combination with bronchial arterial infusion for treatment of advanced non-small-cell lung cancer, one year follow-up 2009

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Chapter Ref. Authors Title Year
Ethics [1] Joël Rosnay Biologie de synthèse: Enjeux et défis pour l’humanité 2004
Ethics [2] Synbiosafe 2008
Ethics [3] Bernadette Bensaude Vincent, Dorothée Benoit-Browaeys Petite typologie de la biologie synthétique et enjeux éthiques 2009
Ethics [4] Anna Deplazes Æ Markus Huppenbauer Synthetic organisms and living machines 2004
Ethics [5] Schmidt M, Ganguli-Mitra A,and al. A priority paper for the societal and ethical aspects of synthetic biology 2009
Ethics [6] Parens E, Johnston J, Moses J. Ethics. Do we need "synthetic bioethics"? 2009

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Chapter Ref. Authors Title Year
Safety [1] Jonathan B. Tucker and al. The Promise and Perils of Synthetic Biology 2006
Safety [2] Synbiosafe 2008
Safety [3] Vivagora 2009
Safety [4] New Atlantis 2004

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