Team:IBB Pune/project/systems together

From 2009.igem.org

(Difference between revisions)
 
(2 intermediate revisions not shown)
Line 3: Line 3:
-
=='' Master Plan'' ==
+
<html><p><span style="font-weight:bold; font-size:200%; color:#0000cc;">Master Plan</span></p></html>
-
 
+
<html><p><span style="font-weight:bold; font-size:125%; color:#FF6600;">Constructing multi-strain computational modules using Nucleotide and Protein mediated cell-cell signaling</span></p></html>
-
 
+
-
'''Constructing multi-strain computational modules using Nucleotide and Protein mediated cell-cell signaling'''
+
-
 
+
Building complex genetic circuits in a single cell becomes difficult due to the formidable task of co-transforming large nucleotide sequences in addition to the imposed metabolic burden on the cell. Can a complex system be divided into independent modules that reside in different cells and interact with each other using nucleotide and protein mediated cell-cell signalling to act as a single unit? We seek to address this problem using a three pronged approach.  
Building complex genetic circuits in a single cell becomes difficult due to the formidable task of co-transforming large nucleotide sequences in addition to the imposed metabolic burden on the cell. Can a complex system be divided into independent modules that reside in different cells and interact with each other using nucleotide and protein mediated cell-cell signalling to act as a single unit? We seek to address this problem using a three pronged approach.  

Latest revision as of 02:26, 22 October 2009





Master Plan

Constructing multi-strain computational modules using Nucleotide and Protein mediated cell-cell signaling

Building complex genetic circuits in a single cell becomes difficult due to the formidable task of co-transforming large nucleotide sequences in addition to the imposed metabolic burden on the cell. Can a complex system be divided into independent modules that reside in different cells and interact with each other using nucleotide and protein mediated cell-cell signalling to act as a single unit? We seek to address this problem using a three pronged approach.

Firstly, we are trying to introduce natural competance genes into the biobrick framework which will act as nucleotide importers.

Secondly, we are building a protein export system using the TAT dependent export pathway.

Finally, we are attempting to construct a multi-state turing machine which is a compound, modular computational system that has independent, interacting states which applies the above principle. We hope that this approach overcomes the obstacles in building more complex and composite circuits.

Retrieved from "http://2009.igem.org/Team:IBB_Pune/project/systems_together"