From 2009.igem.org
(Difference between revisions)
|
|
| Line 3: |
Line 3: |
| | | | |
| | | | |
| - | =='' Master Plan'' ==
| + | ='' Master Plan'' = |
| | | | |
| | | | |
Revision as of 09:41, 19 October 2009
- Home
- Team
- Project
Summary
Details
Results
Modeling
- Related
- Safety
- Parts
- Notebook
Master Plan
Constructing multi-strain computational modules using Nucleotide and Protein mediated cell-cell signaling
Building complex genetic circuits in a single cell becomes difficult due to the formidable task of co-transforming large nucleotide sequences in addition to the imposed metabolic burden on the cell. Can a complex system be divided into independent modules that reside in different cells and interact with each other using nucleotide and protein mediated cell-cell signalling to act as a single unit? We seek to address this problem using a three pronged approach.
Firstly, we are trying to introduce natural competance genes into the biobrick framework which will act as nucleotide importers.
Secondly, we are building a protein export system using the TAT dependent export pathway.
Finally, we are attempting to construct a multi-state turing machine which is a compound, modular computational system that has independent, interacting states which applies the above principle. We hope that this approach overcomes the obstacles in building more complex and composite circuits.
"
