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| - | {{Template:TUDelftiGEM2009}} | + | {{Template:TUDelftiGEM2009_menu_Model}} |
| - | <br>
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| - | ='''Delay Device'''=
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| - | [[Image:Negative Feedforward.jpg]]<br>
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| - | Figure 1: Negative Feedforward model<br>
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| - | [[Image:Riboregulator_delay.jpg]]<br>
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| - | Figure 2: Riboregulator model<br>
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| - | ==Mathematical Modeling==
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| - | The Negative Feedforward model shown above can be expressed with the following set of ODEs (ordinary differential equations):<br>
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| - | [[Image:negative_feedforward_ODEs_2.jpg]]<br><br>
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| - | The Riboregulator model shown above can be expressed with the following set of ODEs:<br>
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| - | [[Image:riboregulator_ODEs.jpg]]<br><br>
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| - | The symbols in this system of equations are found in the table below:<br>
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| - | [[Image:symbols_table.jpg]]<br><br>
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| - | We would like to give credit to the [https://2008.igem.org/Team:Bologna/Modeling Bologna '08 team] and [https://2008.igem.org/Team:UNIPV-Pavia/Modeling UNIPV-Pavia '08 team], who's project was useful in determining our own equations.
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| - | ='''Conjugation'''=
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| - | Using the paper "[http://www3.interscience.wiley.com/journal/118837812/abstract?CRETRY=1&SRETRY=0 A model for bacterial conjugal gene transfer on solid surfaces]", we established the assumptions and parameters that would be needed for the .
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| - | =='''Assumptions'''==
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| | | | |
| - | =='''Parameters'''==
| + | ='''Modeling'''= |
| - | *Surface area of media (A)
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| - | *Initial colony radius (r_0)
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| - | *Specific growth rate (g_n)
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| - | *Colony radial growth rate (g_r)
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| - | *Maximum numbers of cells sustained by system (N_max)
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| - | *Initial number of donors (N_d) and recipients (N_r)
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| - | All these parameters can be determined experimentally, or by literary research into previous conjugation experiments.
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| - | =='''Spatial distribution of bacteria'''==
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| | | | |
| - | =='''Growth of colonies'''==
| + | Please select one of the two modeling sections: [[Team:TUDelft/Modeling_Cascade |Transcriptional Cascade Modeling]] or [[Team:TUDelft/Modeling_Conjugation |Conjugation Modeling]]. |
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| - | =='''Contact between colonies'''== | + | <html> |
| - | | + | <table border=0> |
| - | =='''Conjugation modeling'''== | + | <tr> |
| - | | + | <td> |
| - | =='''Final cell number'''== | + | <a border=0 href=https://2009.igem.org/Team:TUDelft/Modeling_Cascade><img src=https://static.igem.org/mediawiki/2009/f/f9/TUDtranscriptmodelani.gif></a> |
| | + | </td> |
| | + | <td> |
| | + | <img src=https://static.igem.org/mediawiki/2009/f/f1/TUD1pxspacer.png width=40px> |
| | + | </td> |
| | + | <td> |
| | + | <a border=0 href=https://2009.igem.org/Team:TUDelft/Modeling_Conjugation><img src=https://static.igem.org/mediawiki/2009/2/21/TUDconjmodelani.gif></a> |
| | + | </td> |
| | + | </tr> |
| | + | </table> |
| | | | |
| | + | </html> |
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| | {{Template:TUDelftiGEM2009_end}} | | {{Template:TUDelftiGEM2009_end}} |
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