Team:Paris

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iGEM Paris Team

Hello everyone! welcome to our wiki. It's the 3rd year for the Paris Team and we're still motivated to do our best. This year we're a team of 13 students (what a luck). We are 6 biologists, 2 mathematicians, 1 computer scientist, 1 sociologist, 1 infectiologist, 1 geneticist, and 1 chemist. We've got the best of the best of the best supervisors like Ariel Lindner, Guillaume Cambray and Samuel Bottani. So... let's the contest begin! (See our team here).

Our project - A Message in a Bubble

We aimed at developing a long distance communication system between gram-negative bacteria that is based on the ability of these organisms to produce Outer-Membrane Vesicles (OMVs). We designed a framework which can be easily expanded to a lot of different inputs/ouputs. We hope this standardized approach will increase our capacity to manipulate information and/or matter exchange between bacterial cells. This can be used in any engineered biological process requiring transformation or a transfer information system, including medical applications and bio-remediation.

We tried to standardize:

• i/ the increase of vesicle production;
• ii/ the system to address proteins to these vesicles;
• iii/ their fusion with target bacteria. You can find detailled information in our OMV Project description or in our different parts.

By analogy to the Internet Protocol, we called our process a Bacterial Protocol. We found that the title Message in a bubble described it quite nicely.

For more information on how we came up with this idea, please have a look at our brainstorming area.

News

• 30th July : Input Primers and Strain on the Wiki page here and here
• 23th July : First participation of the team in a popularization of science event in Paris.
• 22th July : Let's start our Informatic tool for Labs manipulation on iPhone. see here.
• 21th July : template site seems not to work well with IE and FF&Co, so we've got to change some BG but it's not essential right now
• 20th July : Team image presentation is finish, now let's see what everyone gonna put in it.... Beginning of Labs work !! (finaly)
• 15th July : NoteBook works, now we've got to fill it with some writting
• 14th July : Hello ! The Wiki is under construction you may see some funny things, don't worry we'll be functional soon.

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