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Team:Paris
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iGEM Paris Team
Hello everyone! welcome to our wiki. It's the 3rd year for the Paris Team and we're still motivated to do our best. This year we have a team of 13 students (what a luck). We are 6 biologists, 2 mathematicians, 1 computer scientist, 1 sociologist, 1 infectiologist, 1 geneticist, and 1 chemist. We've got the best of the best of the best supervisors like Ariel Lindner, Guillaume Cambray and Samuel Bottani. So... let's the contest begin! (See our team here).
Our project - A Message in a Bubble
We aimed developing a long distance communication system between gram-negative bacteria that is based on the ability of these organisms to produce Outer-Membrane Vesicles (OMVs). We designed a framework which can be easily expanded to a lot of different inputs/ouputs. We hope this standardized approach will increase our capacity to manipulate information and/or exchange it between bacteria. This can be used in any engineered biological process requiring transformation or a system of information transfer, including medical applications and bio-remediation.
We tried to standardize:
- i/ the increase of vesicle production;
- ii/ the system to address proteins to these vesicles;
- iii/ their fusion with target bacteria. You can find detailed information in our OMV Project description or in our different parts.
By analogy to the Internet Protocol, we called our process a Bacterial Protocol. We found that the title Message in a bubble described it quite nicely. In a simple way, the comprehension of vesicles process sounds like a build of a bacteria language.
For more information on how we came up with this idea, please have a look at our brainstorming area.
Sponsor Award
Visitors & Collaborations
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