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Team:Paris/Transduction modeling
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iGEM > Paris > Reception > Modeling
Contents |
Modeling
Overview
Our reception system uses the fec operon in order to transmit the signal received on the outer memebrane via the vesicules into the cytoplasm to induce a response from the reception cells. Once the vesicule has fusioned with the cell, the FecA molecule present on the previous vesicule wall activates the FecR molecule on the inner membrane ; then, thranks the FecI transcription factor, the pFec promoter is ON and transcription can start. The plasmid of this reception cell was designed to produce a positive reaction once the signal is received so that, even with a very faint signal (very very few FecA molecules inside the vesicules), the reception population will be activated. To this end, we placed and
The Fec System as used in our system
Chemical Equations
Kinetics Equations
Stochastic and Deterministic Simulations
Results and discussion
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