Team:Paris/Transduction overview strategy

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Contents 1 Overview 1.1 C. Our Strategy 1.1.1 B.1 ? 1.1.2 C.2 The trick TCS

Overview

• Introduction
• A. Fusion
  • A.1 jun/fos
  • A.2 G3P
  • A.3 Snares
• B. Our strategy
• C. Construction

C. Our Strategy

B.1 ?

euh

C.2 The trick TCS

We could ,with the help of Alfonso Jaramillo, design a synthetic PBP which could detect the substrate we choosed and activate a specific HK. The previous work done by Valencia in 2006 was to design vanilin-sensitive PBP and a network for a graduated response whereas we just need a proteic sensitive PBP and a binary type of response.

Even if the idea of creating a synthethic protein was very attractive, it would have been difficult to have concrete result in just 3 months.