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Team:Groningen
From 2009.igem.org
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| + | <h1>Heavy metal scavengers<!-- with a vertical gas drive--></h1> | ||
| + | Human health and the environment are endangered by heavy metal pollution in water and sediment. To battle this problem a '''purification strategy''', in which arsenic, zinc and copper are removed from water and sediment, was developed. This strategy encompasses a biological device in which <i>E. coli</i> bacteria accumulate metal ions from solutions, after which they '''produce gas vesicles''' and '''start floating'''. This biological device consists of two integrated systems: one for metal uptake and storage, the other for metal induced buoyancy. The uptake and storage system consists of a [[Team:Groningen/Project/Transport|metal transporter]] and [[Team:Groningen/Project/Accumulation|metal binding proteins]] (to reduce toxicity and increase accumulation). The buoyancy system is made up of a [[Team:Groningen/Project/Promoters|metal induced promotor]] in front of a [[Team:Groningen/Project/Vesicle|gas vesicle gene cluster]]. The combination of both systems will enable the efficient cleaning of polluted water and sediment in a biological manner. | ||
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| + | |style="vertical-align:top;"|''Please fill out our ethics survey!'' | ||
| + | |{{linkedImage|GroningenHumanPractice.png|Team:Groningen/HumanPractice}} | ||
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| + | </div> | ||
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{{imageMap|imap|/wiki/images/8/89/Arsenic_Filtering_System.png|610|410| | {{imageMap|imap|/wiki/images/8/89/Arsenic_Filtering_System.png|610|410| | ||
{{imageMapLink|arsenic|35|0|149|77|/wiki/images/2/2d/Arsenic_Filtering_System_-_Arsenic.png}} | {{imageMapLink|arsenic|35|0|149|77|/wiki/images/2/2d/Arsenic_Filtering_System_-_Arsenic.png}} | ||
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{{imageMapLink|gas|401|86|137|106|/wiki/images/7/72/Arsenic_Filtering_System_-_Gas_Vesicles.png}} | {{imageMapLink|gas|401|86|137|106|/wiki/images/7/72/Arsenic_Filtering_System_-_Gas_Vesicles.png}} | ||
{{imageMapLink|promoter|114|295|168|63|/wiki/images/5/5c/Arsenic_Filtering_System_-_Promoter.png}} | {{imageMapLink|promoter|114|295|168|63|/wiki/images/5/5c/Arsenic_Filtering_System_-_Promoter.png}} | ||
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| - | <div id="imap"><div style="position:absolute;bottom:31px;right:72px;">{{linkedImage|Next.JPG|Team:Groningen/Project/Transport}}</div> | + | <div id="imap" style="position:absolute;right:0px;"><div style="position:absolute;bottom:31px;right:72px;">{{linkedImage|Next.JPG|Team:Groningen/Project/Transport}}</div> |
<html><ul> | <html><ul> | ||
<li id="arsenic"></html>It all starts with [[Team:Groningen/Vision|arsenic]] in solution.<html></li> | <li id="arsenic"></html>It all starts with [[Team:Groningen/Vision|arsenic]] in solution.<html></li> | ||
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<li id="promoter"></html>[[Team:Groningen/Project/Promoters|Metal sensitive promoters]]<html></li> | <li id="promoter"></html>[[Team:Groningen/Project/Promoters|Metal sensitive promoters]]<html></li> | ||
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| + | <div style="float:left;border:solid 1px black;"> [[Image:The_city_of_Talent.jpg|[http://www.cityoftalent.nl/en The City of Talent]|250px]]<br> | ||
| + | <html><a id="csb" href="http://www.centreforsyntheticbiology.eu/"><img width="150" src="https://static.igem.org/mediawiki/igem.org/b/b0/Groningen2008_RUG_CSB.png" /></a><br> | ||
| + | <a id="DSM" href="http://www.dsm.com"><img style="width: 250px; height: 65px" src="https://static.igem.org/mediawiki/2009/7/7c/DSM-logo.png"></a> | ||
| + | <br><a id="SBGG" href="http://www.sbgg.nl/"><img src="http://www.sbgg.nl/style/img/logo.gif"></a> | ||
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Revision as of 10:48, 16 September 2009
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Heavy metal scavengersHuman health and the environment are endangered by heavy metal pollution in water and sediment. To battle this problem a purification strategy, in which arsenic, zinc and copper are removed from water and sediment, was developed. This strategy encompasses a biological device in which E. coli bacteria accumulate metal ions from solutions, after which they produce gas vesicles and start floating. This biological device consists of two integrated systems: one for metal uptake and storage, the other for metal induced buoyancy. The uptake and storage system consists of a metal transporter and metal binding proteins (to reduce toxicity and increase accumulation). The buoyancy system is made up of a metal induced promotor in front of a gas vesicle gene cluster. The combination of both systems will enable the efficient cleaning of polluted water and sediment in a biological manner.
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